Evidence map›Paper›PMID 39844940›Full record

ArticleProceedings. IEEE International Symposium on Biomedical Imaging2024

ENHANCING TRANSCRANIAL FOCUSED ULTRASOUND TREATMENT PLANNING WITH SYNTHETIC CT FROM ULTRA-SHORT ECHO TIME (UTE) MRI: A MULTI-TASK DEEP LEARNING APPROACH.

Dong Liu, Zhuoyao Xin, Robin Ji, Fotis Tsitsos, Sergio Jiménez-Gambín, Elisa E Konofagou, Vincent P Ferrera, Jia Guo

Abstract read
In one paragraph

Article in Proceedings. IEEE International Symposium on Biomedical Imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dong LiuZuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.
Zhuoyao XinF.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.
Robin JiDepartment of Biomedical Engineering, Columbia University, New York, NY, USA.
Fotis TsitsosDepartment of Biomedical Engineering, Columbia University, New York, NY, USA.
Sergio Jiménez-GambínDepartment of Biomedical Engineering, Columbia University, New York, NY, USA.
Elisa E KonofagouDepartment of Biomedical Engineering, Columbia University, New York, NY, USA.
Vincent P FerreraZuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.
Jia GuoZuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.

Funding

Focused ultrasound for memory disordersR01MH133020 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI VINCENT P FERRERA, Elisa E. Konofagou · 2023 to 2026
$3.1M
NIMH NIH HHS R01 MH133020
6 · The paper itself

Abstract

Utilizing a multi-task deep learning framework, this study generated synthetic CT (sCT) images from a limited dataset of Ultrashort echo time (UTE) MRI for transcranial focused ultrasound (tFUS) planning. A 3D Transformer U-Net was employed to produce sCT images that closely replicated actual CT scans, demonstrated by an average Dice coefficient of 0.868 for morphological accuracy. The acoustic simulation with sCT images showed mean focus absolute pressure differences of 8.85±7.29 % for the anterior cingulate cortex, 11.81±8.63 % for the precuneus, and 7.27±3.64 % for the supplemental motor cortex, with focus position discrepancies within 0.9±0.5 mm. These results underscore the efficacy of UTE-MRI as a non-radiative, cost-effective alternative for tFUS planning, with significant potential for clinical application.

Indexed as

Acoustic simulationDeep learningSynthetic CTTranscranial focused ultrasound therapyUltrashort Echo time MRI

Identifiers

PMID39844940
PMCPMC11753620

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.