ArticleJAC-antimicrobial resistance2025
Resistance to empirical antibiotics in urinary tract infections caused by Enterobacterales in the East of England.
Article in JAC-antimicrobial resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Evaluation of the Lodestar DX: a comparison with traditional culture for the detection of bacteriuria in the workup of urinary tract infection.JAC-antimicrobial resistance · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: To characterize resistance rates in urinary tract infections caused by Enterobacterales to first- and second-line antibiotics. Methods: Positive urine cultures examined by the Eastern Pathology Alliance network from September 2018 to September 2023 were retrospectively analysed. Enterobacterales from non-pregnant adults were included. Resistance to cefalexin, nitrofurantoin, trimethoprim, pivmecillinam and fosfomycin was investigated. Results: A total of 193 137 samples from 99 635 patients met inclusion criteria. The mean number of episodes per patient was 1.94, with a range of 1-55 episodes over the 5 year period. Patients were predominantly of female sex (76.6%) and of an older age (mean age 66.4 ± 19.5 SD). Conclusions: This study illustrates resistance rates to commonly prescribed antibiotics for urinary tract infections in Norfolk and Waveney. Adjustments to local empirical antibiotic guidelines have been shaped by the resistance rates demonstrated herein.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.