Evidence map›Paper›PMID 39844889›Full record

ArticleClinical case reports2025

Defying the Odds: A Case of Successfully Treated Harlequin Ichthyosis in Lebanon.

Bassel Hamam, Sarah Saleh, Miled Yaacoub, Houssein Chebbo, Sarah Jalloul, Karam Karam, Rima Houmani

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bassel HamamDepartment of Radiology University of Balamand Balamand Lebanon.
Sarah SalehFaculty of Medicine University of Balamand Balamand Lebanon.
Miled YaacoubFaculty of Medicine University of Balamand Balamand Lebanon.
Houssein ChebboFaculty of Medicine University of Balamand Balamand Lebanon.ORCID https://orcid.org/0009-0008-2184-3599
Sarah JalloulDepartment of Gastroenterology, Faculty of Medicine University of Balamand Balamand Lebanon.
Karam KaramDepartment of Gastroenterology, Faculty of Medicine University of Balamand Balamand Lebanon.ORCID https://orcid.org/0009-0001-1914-320X
Rima HoumaniDepartment of Obstetrics and Gynecology Lebanese University Beirut Lebanon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Harlequin ichthyosis is a rare skin disorder affecting newborns characterized by a scaly skin, flexed limbs, ectropium, and eclabium. The overall incidence of HI is 1 in 300,000 births, with approximately only 200 cases reported worldwide. Some studies uncovered a TH17 immune skewing in patients with HI, which is also seen in psoriasis. We herein present a case of a newborn found to have harlequin ichthyosis, whom his mother is known to have psoriasis. The baby was treated with topical antibiotics and retinoid creams. The baby then exhibited smoother skin with less scaling and flatter fissures.

Indexed as

case reportharlequin ichthyosishyperkeratotic scalesretinoid creamstopical antibiotics

Identifiers

PMID39844889
PMCPMC11752141

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.