ReviewBiomaterials research2025
Bioactive Glasses: Advancing Skin Tissue Repair through Multifunctional Mechanisms and Innovations.
Review in Biomaterials research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy of bioactive glass versus traditional bone grafts in maxillofacial reconstruction: A systematic review and meta-analysis of clinical outcomes.Cell transplantationPooled it
- Bioactive glasses-mediated ion therapy ameliorates hepatic osteodystrophy by reprogramming the liver-bone axis.Bioactive materials · 2027Article
- Effects of gallium and clove oil embedded in porous phosphate coacervate glass fibres on wound healing.Materials advances · 2026Article
- Article
- Bioactive glass nanoparticles induce pronounced cytotoxicity in human hepatocellular carcinoma Hep-G2 cells through ROS-mediated genomic instability and mitochondrial apoptosis.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Bioactive glass nanoparticles induce intrinsic p53-dependent apoptosis and promote genomic instability via ROS overproduction and mitochondrial depolarization in triple-negative breast cancer cells.Scientific reports · 2026Article
- Mesoporous bioactive glass-recombinant collagen III nanocomposite capsule promotes skin wound healing via adaptive immune modulation.Regenerative biomaterials · 2026Article
- Bioglasses Versus Bioactive Calcium Phosphate Derivatives as Advanced Ceramics in Tissue Engineering: Comparative and Comprehensive Study, Current Trends, and Innovative Solutions.Journal of functional biomaterials · 2025Review
- Zinc Peroxide-Mediated In Situ Forming Hydrogels for Endogenous Tissue Regeneration.Biomaterials research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As a complex and dynamically regulated process, wound healing is collaboratively carried out by multiple types of cells. However, the precise mechanisms by which these cells contribute to immune regulation are not yet fully understood. Although research on bone regeneration has been quite extensive, the application of bioactive glass (BG) in skin tissue repair remains still relatively underexplored. The review focuses on the principles and the latest progress of using BGs for skin tissue repair, highlighting BGs' special performance requirements, including biological activity, biocompatibility, biodegradability, and antibacterial properties, emphasizing their potential for skin tissue repair. In addition, BGs play a substantial role in regulating various inflammatory cells (neutrophils, macrophages, mast cells, etc.) and tissue repair cells [fibroblasts, vascular endothelial cells, mesenchymal stem cells (MSCs), etc.] involved in wound healing. The review also covers recent developments in composite materials incorporating BGs, demonstrating their ability to promote angiogenesis, inhibit wound biofilms, and improve inflammatory responses in chronic wounds. Furthermore, BGs have shown effectiveness in promoting epithelial regeneration and collagen deposition in burn wounds as well as their applications in scar management and post-tumor resection wound care. Finally, we summarize our views on challenges and directions in the emerging field of BGs for skin tissue regeneration research in the future.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.