ArticleFrontiers in neuroscience2024
Mapping subcortical brain lesions, behavioral and acoustic analysis for early assessment of subacute stroke patients with dysarthria.
Article in Frontiers in neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Investigating acoustic startle priming-induced cortical network reorganization in post-stroke dysarthria: a fNIRS study.Biomedical optics express · 2026Article
- Association between the timing of chewable complementary food introduction and functional speech disorders in children: a case-control study.Frontiers in pediatrics · 2026Article
- Cortical morphological changes in stroke-associated dysarthria patients.Frontiers in neurologyArticle
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Authors and funding
9 authors.
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Abstract
Introduction: Dysarthria is a motor speech disorder frequently associated with subcortical damage. However, the precise roles of the subcortical nuclei, particularly the basal ganglia and thalamus, in the speech production process remain poorly understood. Methods: The present study aimed to better understand their roles by mapping neuroimaging, behavioral, and speech data obtained from subacute stroke patients with subcortical lesions. Multivariate lesion-symptom mapping and voxel-based morphometry methods were employed to correlate lesions in the basal ganglia and thalamus with speech production, with emphases on linguistic processing and articulation. Results: The present findings revealed that the left thalamus and putamen are significantly correlated with concept preparation ( Discussion: The present study provides a nuanced understanding of how lesions in the basal ganglia and thalamus impact various stages of speech production, thereby enhancing our understanding of the subcortical neuromechanisms underlying dysarthria. The findings could also contribute to the identification of multimodal assessment indicators, which could aid in the precise evaluation and personalized treatment of speech impairments.
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