Evidence map›Paper›PMID 39844433›Full record

ArticleCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2025

Elastic Recoil and Deployment Asymmetry of the Transcatheter Heart Valve in Bicuspid Versus Tricuspid Anatomy.

Odette Iskandar, Habib Layoun, Shivabalan Kathavarayan Ramu, Judah Rajendran Ravi Raja Malar Vannan, Elian Abou Asala, Jaideep Singh Bhalla, Elizabeth Ghandakly, Besir Besir, James Yun, Grant Reed and 4 more

Abstract readComparative Study
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In one paragraph

Article in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Odette IskandarDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Habib LayounDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Shivabalan Kathavarayan RamuDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Judah Rajendran Ravi Raja Malar VannanDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Elian Abou AsalaDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Jaideep Singh BhallaDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Elizabeth GhandaklyDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Besir BesirDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
James YunDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Grant ReedDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Rishi PuriDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Serge HarbDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Amar KrishnaswamyDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.ORCID 0000-0001-6048-7955
Samir R KapadiaDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.ORCID 0000-0002-0026-3391

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

backgroundData supporting the use of transcatheter aortic valve replacement (TAVR) for bicuspid aortic valve (BAV) is limited compared to tricuspid aortic valve (TAV) anatomy, as the BAV anatomy poses unique challenges to prosthesis expansion and symmetric deployment.

aimsWe aim to compare the acute recoil and asymmetry of the SAPIEN-3 valve between BAV and TAV anatomies and their impact on procedural outcomes.

methodsWe conducted a single-center study of patients who underwent TAVR with the SAPIEN-3 valve. We measured acute recoil, deployment asymmetry, and length asymmetry from intraprocedural angiogram before and after postdilation, as well as before and after predilation. Hemodynamic and procedural outcomes were studied.

resultsAmong 946 patients, 9% had BAV. In the RAO view, BAV patients had significantly higher absolute and relative acute recoil across all diameters, while in the LAO view, only central diameter relative recoil was significantly higher (p < 0.001). Deployment asymmetry was more common in BAV patients with an OR of 1.88 (CI 1.19, 2.96; p = 0.01). Predilation reduced both length and deployment asymmetry in RAO and LAO views for TAV and BAV patients (p < 0.001). Postdilation significantly reduced acute valve recoil in both groups (p = 0.002 and p = 0.032). Hemodynamic outcomes were comparable between TAV and BAV patients, and there were no significant associations between deployment or length asymmetry and procedural outcomes.

conclusionsAcute recoil, deployment asymmetry, and length asymmetry are common in BAV patients but do not affect short-term clinical outcomes or hemodynamics.

Indexed as

Aortic ValveAortic Valve StenosisHeart Valve DiseasesHeart Valve ProsthesisTranscatheter Aortic Valve ReplacementTricuspid ValveAgedAged, 80 and overBicuspid Aortic Valve DiseaseElasticityFemaleHemodynamicsHumansMaleProsthesis DesignRetrospective Studiesacute elastic recoildeployment asymmetrylength asymmetrytranscatheter aortic valve replacement

Identifiers

PMID39844433
PMCPMC11962825

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.