Evidence map›Paper›PMID 39844328›Full record

ArticleEuropean journal of medical research2025

Multifidus fat infiltration negatively influences the postoperative outcomes in lumbar disc herniation following transforaminal approach percutaneous endoscopic lumbar discectomy.

Kai Sun, Renjie Qin, Wenzhuo Wang, Genlong Jiao, Guodong Sun, Guoliang Chen, Jun Li

Abstract read
In one paragraph

Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Letter to the Editor concerning "Risk factors for recurrent lumbar disc herniation after percutaneous endoscopic lumbar discectomy: roles of spinopelvic parameters and facet joint degeneration" by Xiangdong Gong, et al. (Eur Spine J [2026]; doi: 10.1007/s00586-026-10111-2).European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Review
  3. Role of paraspinal muscle fatty infiltration in predicting adjacent segment disease after lumbar spinal fusion: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kai Sun *Department of Orthopedic Surgery, The Fifth Affiliated Hospital of Jinan University (Hayuan Shenhe Peolple's Hospital), Heyuan, 517400, China.
Renjie Qin *Department of Orthopedic Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Wenzhuo Wang *Department of Orthopedic Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Genlong JiaoDepartment of Orthopedic Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Guodong SunDepartment of Orthopedic Surgery, Jiujiang University Clinical Medical College (Jiujiang University Affiliated Hospital), Jiujiang, 332006, China. sunguodong1631014@163.com.
Guoliang ChenDepartment of Orthopedic Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China. chenguoliang@jnu.edu.cn.
Jun LiDepartment of Orthopedic Surgery, Jiujiang University Clinical Medical College (Jiujiang University Affiliated Hospital), Jiujiang, 332006, China. 937348676@qq.com.

Funding

Dongguan Science and Technology of Social Development Program 20231800939902Fundamental Research Funds for the Central Universities 21623310Guangdong Basic and Applied Basic Research Foundation 2022A1515140171Jiangxi Province Health Science and Technology Program 202311519Medical Joint Fund of Jinan University YXJC2022011Science and Technology Projects in Guangzhou SL2023A03J0570, 2024A04J4323
6 · The paper itself

Abstract

purposeThis study aims to investigate the influence of multifidus muscle fat infiltration on clinical outcomes in lumbar disc herniation (LDH) undergoing percutaneous endoscopic lumbar discectomy (PELD).

methodsA retrospective analysis was conducted on 224 patients who underwent lateral PELD, with complete one-year follow-up data. Patients were divided into two groups based on preoperative MRI evaluation of L4 multifidus muscle fat infiltration: a mild group (< 25%) and a severe group (≥ 25%). Baseline characteristics and postoperative outcomes were recorded and compared.

resultsAt the final follow-up, significant improvements in VAS scores for back and leg pain, ODI scores, and EQ-5D scores were observed in both groups. There were no statistically significant differences in preoperative VAS scores for back and leg pain, ODI scores, and EQ-5D scores between the two groups. However, significant differences were found in VAS scores for back pain, ODI scores, and EQ-5D scores at 3, 6, and 12 months postoperatively (P < 0.05), while no significant difference was noted in VAS scores for leg pain during follow-up. The total recurrence rate was 6.7% (15 out of 224 cases), with 12 cases in the severe group and 3 cases in the mild group, showing a statistically significant difference (P < 0.05).

conclusionThe effectiveness of postoperative PELD in patients with LDH is impacted by severe multifidus muscle fat infiltration. Multifidus muscle fat infiltration represents a risk factor for recurrent LDH after PELD.

Indexed as

Adipose TissueDiskectomy, PercutaneousEndoscopyIntervertebral Disc DisplacementLumbar VertebraeParaspinal MusclesAdultFemaleFollow-Up StudiesHumansMagnetic Resonance ImagingMaleMiddle AgedRetrospective StudiesTreatment OutcomeLumbar disc herniationMultifidus muscle fat infiltrationPercutaneous endoscopic lumbar discectomy

Identifiers

PMID39844328
PMCPMC11756129

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.