Evidence map›Paper›PMID 39844203›Full record

SynthesisBMC research notes2025

Interrupted time series datasets from studies investigating the impact of interventions or exposures in public health and social science: a data note.

Simon L Turner, Elizabeth Korevaar, Amalia Karahalios, Andrew B Forbes, Joanne E McKenzie

Abstract readMeta-Analysis
In one paragraph

Synthesis in BMC research notes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Simon L TurnerSchool of Public Health and Preventive Medicine, Monash University, Level 4, 553 St Kilda Road, Melbourne, VIC, 3004, Australia.ORCID http://orcid.org/0000-0001-9163-4524
Elizabeth KorevaarSchool of Public Health and Preventive Medicine, Monash University, Level 4, 553 St Kilda Road, Melbourne, VIC, 3004, Australia.ORCID http://orcid.org/0000-0001-5808-7813
Amalia KarahaliosCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC, 3010, Australia.ORCID http://orcid.org/0000-0002-7497-1681
Andrew B ForbesSchool of Public Health and Preventive Medicine, Monash University, Level 4, 553 St Kilda Road, Melbourne, VIC, 3004, Australia.ORCID http://orcid.org/0000-0003-4269-914X
Joanne E McKenzieSchool of Public Health and Preventive Medicine, Monash University, Level 4, 553 St Kilda Road, Melbourne, VIC, 3004, Australia. joanne.mckenzie@monash.edu.ORCID http://orcid.org/0000-0003-3534-1641

Funding

NHMRC career development fellowship GNT1143429NHMRC investigator grant GNT2009612NHMRC project grant 1145273
6 · The paper itself

Abstract

objectivesThe interrupted time series (ITS) design is commonly used to investigate the impact of an intervention or exposure in public health. There are many statistical methods that can be used to analyse ITS data and to meta-analyse their results. We undertook two empirical studies to investigate: (i) how effect estimates (and associated statistics) compared when six statistical methods were applied to 190 real-world datasets; and (ii) how meta-analysis effect estimates (and associated statistics) compared when the combinations of two ITS analysis methods and five meta-analysis methods were applied to 17 real-world meta-analyses including 283 ITS datasets. Here we present a curated repository of a subset of ITS datasets from these studies. DATA DESCRIPTION: The repository includes 430 ITS datasets curated from the two empirical studies. The datasets are diverse in the populations, interruptions and outcomes examined, and are methodologically diverse in the outcome types, aggregation time intervals, number of timepoints and segments. Most of the datasets are from public health. For each dataset, we provide the outcome value at each timepoint and the segment (indicating different interruptions), along with characteristics of the dataset. This repository may be of value for future research of ITS studies, and as a source of examples of ITS for use in teaching.

Indexed as

Interrupted Time Series AnalysisPublic HealthSocial SciencesHumansEmpirical evaluationInterrupted time seriesMeta-analysisPublic health

Identifiers

PMID39844203
PMCPMC11755864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.