ArticleBMC oral health2025
Classification and prognostic evaluation of ameloblastoma using multiplanar CT imaging: a retrospective analysis.
Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- [Sinonasal ameloblastoma: Clinical case presentation and literature review].Revista medica del Instituto Mexicano del Seguro Social · 2026Review
- Long-Term Clinical Outcome of a Surgically Treated Ameloblastoma: Over a Decade of Follow-Up and Oral Rehabilitation.Dentistry journal · 2026Article
- Ameloblastic carcinoma with isolated supramandibular lymph node metastasis in an adolescent: a case report and review of the literature.Frontiers in oncology · 2026Article
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6 authors.
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Abstract
backgroundAmeloblastoma is the most prevalent odontogenic tumor of the jaw, with a significant recurrence rate. It was conventionally classified radiographically as unilocular or multilocular. As 3D images become more common, there is a need to reassess this classification. This study aimed to conduct a multi-planar assessment of ameloblastoma using CT images, reclassify the lesions based on locularity, and correlate the locularity with imaging characteristics and recurrence.
methodsPanoramic radiographs and CT images of histopathologically confirmed 255 ameloblastoma patients were included. The analysis encompassed imaging features including locularity, expansion, thinning, cortical perforation, and root resorption. Image characteristics associated with recurrence rate were examined, and image features were assessed based on locularity.
resultsOn panoramic radiographs, most ameloblastomas (68.6%) were classified as multilocular, while 31.4% were unilocular. The CT scan demonstrated that 46.3% of the ameloblastomas were pseudo-multilocular, 29.4% were unilocular, and 24.3% were multilocular. Multilocular cases on panoramic radiographs often appeared as pseudo-multilocular on CT. Cortical perforation, root resorption, and size were significantly correlated with CT locularity types (p < 0.05). The recurrence rate was 14.11%, and the risk of recurrence was substantially reduced by mandibulectomy and a larger tumor size. No other variables were significantly related to recurrence.
conclusionAn accurate diagnosis of ameloblastoma and surgical planning to reduce the recurrence rate are contingent upon the use of three-dimensional imaging modalities, such as CT.
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