Evidence map›Paper›PMID 39843997›Full record

ArticleGut microbes2025

The gut microbiota predicts and time-restricted feeding delays experimental colitis.

Hannah K Ruple, Eva Haasis, Anna Bettenburg, Carina Maier, Carolin Fritz, Laura Schüle, Sarah Löcker, Yvonne Soltow, Lynn Schintgen, Nina S Schmidt and 3 more

Abstract read
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  5. The alleviating effects and mechanisms ofFrontiers in veterinary science · 2025
    Article
  6. Frontiers in immunology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hannah K RupleDepartment of Microbiome Research and Applied Bioinformatics, Institute for Nutritional Sciences, University of Hohenheim, Stuttgart, Germany.
Eva HaasisInstitute of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany.
Anna BettenburgInstitute of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany.
Carina MaierDepartment of Microbiome Research and Applied Bioinformatics, Institute for Nutritional Sciences, University of Hohenheim, Stuttgart, Germany.
Carolin FritzDepartment of Microbiome Research and Applied Bioinformatics, Institute for Nutritional Sciences, University of Hohenheim, Stuttgart, Germany.
Laura SchüleDepartment of Microbiome Research and Applied Bioinformatics, Institute for Nutritional Sciences, University of Hohenheim, Stuttgart, Germany.
Sarah LöckerInstitute of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany.
Yvonne SoltowInstitute of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany.
Lynn SchintgenDepartment of Microbiome Research and Applied Bioinformatics, Institute for Nutritional Sciences, University of Hohenheim, Stuttgart, Germany.
Nina S SchmidtDepartment of Microbiome Research and Applied Bioinformatics, Institute for Nutritional Sciences, University of Hohenheim, Stuttgart, Germany.
Celine SchneiderInstitute of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany.
Axel LorentzInstitute of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany.ORCID 0000-0002-4956-0231
W Florian FrickeDepartment of Microbiome Research and Applied Bioinformatics, Institute for Nutritional Sciences, University of Hohenheim, Stuttgart, Germany.ORCID 0000-0003-1586-0962

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The etiology of inflammatory bowel disease (IBD) remains unclear, treatment options unsatisfactory and disease development difficult to predict for individual patients. Dysbiosis of the gastrointestinal microbiota and disruption of the biological clock have been implicated and studied as diagnostic and therapeutic targets. Here, we examine the relationship of IBD to biological clock and gut microbiota by using the IL-10 deficient (

Indexed as

ColitisGastrointestinal MicrobiomeAnimalsCircadian RhythmDisease Models, AnimalDysbiosisFecesInflammatory Bowel DiseasesInterleukin-10MaleMiceMice, Inbred C57BLMice, KnockoutIL10 protein, mouseInterleukin-10Biological clockcircadian rhythmcolitis predictionexperimental colitisgut microbiotaIBDIL-10inflammatory bowel diseasetime-restricted feeding

Identifiers

PMID39843997
PMCPMC11758946

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.