Evidence map›Paper›PMID 39843963›Full record

Reviewnpj antimicrobials and resistance2024

Unlocking the potential of experimental evolution to study drug resistance in pathogenic fungi.

Stef Jacobs, Giorgio Boccarella, Pieter van den Berg, Patrick Van Dijck, Hans Carolus

Abstract readReview
In one paragraph

Review in npj antimicrobials and resistance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Directed evolution of the pathogenic moldAntimicrobial agents and chemotherapy · 2026
    Article
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  3. Article
  4. Review
  5. Review
  6. Article
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stef JacobsLaboratory of Molecular Cell Biology, Department of Biology, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0001-6535-4051
Giorgio BoccarellaEvolutionary Modelling Group, Department of Biology, KU Leuven, Leuven, Belgium.
Pieter van den BergEvolutionary Modelling Group, Department of Biology, KU Leuven, Leuven, Belgium.
Patrick Van DijckLaboratory of Molecular Cell Biology, Department of Biology, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-1542-897X
Hans CarolusLaboratory of Molecular Cell Biology, Department of Biology, KU Leuven, Leuven, Belgium. hans.carolus@kuleuven.be.ORCID http://orcid.org/0000-0003-1507-3475

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exploring the dynamics and molecular mechanisms of antimicrobial drug resistance provides critical insights for developing effective strategies to combat it. This review highlights the potential of experimental evolution methods to study resistance in pathogenic fungi, drawing on insights from bacteriology and innovative approaches in mycology. We emphasize the versatility of experimental evolution in replicating clinical and environmental scenarios and propose that incorporating evolutionary modelling can enhance our understanding of antifungal resistance evolution. We advocate for a broader application of experimental evolution in medical mycology to improve our still limited understanding of drug resistance in fungi.

Identifiers

PMID39843963
PMCPMC11721431

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.