Evidence map›Paper›PMID 39843924›Full record

Reviewnpj antimicrobials and resistance2024

Drug combinations targeting antibiotic resistance.

Bence Bognár, Réka Spohn, Viktória Lázár

Abstract readReview
In one paragraph

Review in npj antimicrobials and resistance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Repurposing loratadine to reverse colistin resistance inEmerging microbes & infections · 2026
    Article
  2. Review
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  5. Article
  6. Article
  7. Article
  8. Article
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  10. Review
  11. ASP-COMPLEX: redefining antimicrobial stewardship to improve outcomes in high-risk patients with severe infections.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2026
    Review
  12. Repurposing Birabresib to target Gram‑positive bacteria.npj antimicrobials and resistance · 2026
    Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bence BognárHCEMM-BRC Pharmacodynamic Drug Interaction Research Group, Szeged, Hungary.ORCID http://orcid.org/0009-0004-9091-3467
Réka SpohnSynthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.
Viktória LázárHCEMM-BRC Pharmacodynamic Drug Interaction Research Group, Szeged, Hungary. lazar.viktoria@brc.hu.ORCID http://orcid.org/0000-0002-9778-941X

Funding

Magyar Tudományos Akadémia (Hungarian Academy of Sciences) BO/608/21
6 · The paper itself

Abstract

While the rise of antibiotic resistance poses a global health challenge, the development of new antibiotics has slowed down over the past decades. This turned the attention of researchers towards the rational design of drug combination therapies to combat antibiotic resistance. In this review we discuss how drug combinations can exploit the deleterious pleiotropic effects of antibiotic resistance and conclude that each drug interaction has its prospective therapeutic application.

Identifiers

PMID39843924
PMCPMC11721080

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.