Evidence map›Paper›PMID 39843908›Full record

ArticleScientific reports2025

Formation and stability of green and low-cost magnetoliposomes of the soy lecithin, stigmasterol, and β-sitosterol for hyperthermia treatments.

Rosangela Maria Ferreira da Costa E Silva, Ângela Leão Andrade, Erico Tadeu Fraga Freitas, Thalita Marcolan Valverde, Luciano Roni Silva Lara, Darliane Aparecida Martins, Jorge Luis Lopez, Humberto Osório Stumpf, Clésia Cristina Nascentes, Alfredo Miranda de Goes and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rosangela Maria Ferreira da Costa E SilvaUniversidade Estadual de Mato Grosso do Sul, Dourados, MS, CEP 79.804-970, Brazil. rosangela_ferreirafeliz@yahoo.com.br.
Ângela Leão AndradeDepto de Química, ICEB, Universidade Federal de Ouro Preto, UFOP, Ouro Preto, MG, CEP 35400-000, Brazil.
Erico Tadeu Fraga FreitasCentro de Microscopia, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte, MG, CEP 31.270-901, Brazil.
Thalita Marcolan ValverdeDepto de Bioquímica e Imunologia, ICB, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte, MG, CEP 31.270-901, Brazil.
Luciano Roni Silva LaraUniversidade Estadual de Mato Grosso do Sul, Dourados, MS, CEP 79.804-970, Brazil.
Darliane Aparecida MartinsInstituto Federal de Educação, Ciência e Tecnologia do Sul de Minas, Campus Pouso Alegre, Av. Maria da Conceição Santos, 900 - Parque Real, Pouso Alegre, MG, CEP 37550-000, Brazil.
Jorge Luis LopezCentro de Ciências Biológicas e da Natureza, Universidade Federal do Acre, UFAC, Rio Branco, AC, CEP 69.920-900, Brazil.
Humberto Osório StumpfDepto de Química, Universidade Federal de Minas Gerais, Belo Horizonte, MG, CEP 31.270-901, Brazil.
Clésia Cristina NascentesDepto de Química, Universidade Federal de Minas Gerais, Belo Horizonte, MG, CEP 31.270-901, Brazil.
Alfredo Miranda de GoesDepto de Bioquímica e Imunologia, ICB, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte, MG, CEP 31.270-901, Brazil.
Rosana Zacarias DominguesDepto de Química, Universidade Federal de Minas Gerais, Belo Horizonte, MG, CEP 31.270-901, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetoliposomes containing magnetite, soy lecithin, stigmasterol, and beta-sitosterol of the mean size minor than 160 nm were obtained by a scalable and green process using autoclave and sonication without organic solvents. The formation, size of the liposome, linkage, and encapsulation of the magnetite were evaluated by Cryo-TEM. The stability of magnetoliposomes after storage for 6 months at 4 °C was improved by liposome size, the ability of soy lecithin to preserve the magnetite phase against oxidation, pH, polydispersity index, and zeta potential. The iron oxide phase stability was assessed using no conventional X-ray diffraction (high-resolution transmission electron microscopy), energy loss electron spectroscopy, and selected area electron diffraction) in time zero (fresh sample) and 6 months. The high zeta potential measured for magnetoliposomes, │53│ mV, indicated a low tendency to agglomerate. Lip-Fe

Indexed as

Hyperthermia, InducedLecithinsLiposomesSitosterolsStigmasterolCell SurvivalFerrosoferric OxideGlycine maxGreen Chemistry TechnologyHumansParticle SizeFerrosoferric Oxidegamma-sitosterolLecithinsLiposomesSitosterolsStigmasterolCryO-TEMEELSMagnetite stabilitySAEDSoy lecithin liposome

Identifiers

PMID39843908
PMCPMC11754809

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.