SynthesisNature2025
Genomics yields biological and phenotypic insights into bipolar disorder.
Abstract readMeta-Analysis
In one paragraph
Synthesis in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 135 papers, 6 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
135citing papers in PubMed, 6 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
135 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Genome-wide association studies of infant and toddler temperament in European and multi-ancestry populations.Nature human behaviour · 2026Pooled it
- Genome-wide association analyses of borderline personality disorder identify 11 loci and highlight shared risk with mental and somatic disorders.Nature genetics · 2026Pooled it
- Shared genetic architecture of gray matter deficits in schizophrenia and bipolar disorder: evidence from structural neuroimaging-genetic analyses.Psychological medicine · 2026Pooled it
- Lithium effects in the frontolimbic circuitry: a systematic review of neuroimaging findings in bipolar disorder.Translational psychiatry · 2026Pooled it
- Circulating inflammatory proteins associated with risks of schizophrenia, bipolar disorder, and major depressive disorder: a mendelian randomization study.Translational psychiatry · 2025Pooled it
- Pooled it
- Integrative TWAS and multi-omics analyses prioritize HSPE1 as a candidate risk gene for bipolar disorder with immune cell-specific regulatory evidence.European archives of psychiatry and clinical neuroscience · 2026Article
- Big data and psychiatry: advances, constraints and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- GWAS data selection matters in MR: comment on "causal relationship between mental illness and venous thromboembolism: a mendelian randomization study".European archives of psychiatry and clinical neuroscience · 2026Article
- Balancing phenotyping depth and representativeness in psychiatric genomics.Nature genetics · 2026Article
- Exploring the shared genetic architecture and causal relationship between childhood maltreatment and psychiatric disorders.Molecular psychiatry · 2026Article
- Effects of Schizophrenia, Bipolar Disorder, and Depression on Cardiopulmonary and Abdominal Organ Structure.Biological psychiatry global open science · 2026Article
- Article
- Protein-protein interaction network architecture of human polygenic traits reveals domain-spanning connectivity and evolutionary pressures.Genome biology · 2026Article
- Higher frequencies of CNV deletions in bipolar disorder among Chinese Population.Molecular psychiatry · 2026Article
- Dynamic neuro-immune regulation of psychiatric risk loci in human neurons.Nature communications · 2026Article
- Genomic dimensions deconstruct the clinical heterogeneity of bipolar disorder.Research square · 2026Article
- Considering social risk alongside genetic risk for bipolar disorder in the All of Us Research Program.HGG advances · 2026Article
- Polygenic profiles in youth with early-onset psychosis and offspring of schizophrenia or bipolar disorder patients.European child & adolescent psychiatry · 2026Article
- Next-generation precision medicine for mood disorders: reproducible blood biomarkers enable objective diagnostics, subtyping, and targeted therapeutics.Molecular psychiatry · 2026Article
75 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
306 authors.
Kevin S O'ConnellDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway. k.s.oconnell@medisin.uio.no.ORCID http://orcid.org/0000-0002-6865-8795
Maria Koromina *Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Tracey van der Veen *Division of Psychiatry, University College London, London, UK.
Toni Boltz *Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Friederike S David *Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.
Jessica Mei Kay Yang *Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.
Keng-Han Lin *23andMe Inc., Sunnyvale, CA, USA.
Xin Wang *23andMe Inc., Sunnyvale, CA, USA.
Jonathan R I Coleman *Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK.
Brittany L Mitchell *Mental Health and Neuroscience, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Caroline C McGrouther *New York University, New York, NY, USA.
Aaditya V Rangan *New York University, New York, NY, USA.
Penelope A Lind *Mental Health and Neuroscience, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Elise Koch *Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Arvid Harder *Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Nadine Parker *Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Jaroslav Bendl *Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Kristina AdorjanInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.
Esben AgerboiPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
Diego AlbaniDepartment of Neuroscience, Istituto Di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy.
Silvia AlemanyInstituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain.
Ney Alliey-RodriguezDepartment of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA.
Thomas D AlsiPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
Till F M AndlauerDepartment of Neurology, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany.
Anastasia AntoniouNational and Kapodistrian University of Athens, 2nd Department of Psychiatry, Attikon General Hospital, Athens, Greece.
Helga AskPsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway.
Nicholas BassDivision of Psychiatry, University College London, London, UK.
Michael BauerDepartment of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Eva C BeinsInstitute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.
Tim B BigdeliDepartment of Psychiatry and Behavioral Sciences, SUNY Downstate Health Sciences University, Brooklyn, NY, USA.
Carsten Bøcker PederseniPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
Marco P BoksPsychiatry, Brain Center UMC Utrecht, Utrecht, The Netherlands.
Sigrid BørteResearch and Communication Unit for Musculoskeletal Health, Division of Clinical Neuroscience, Oslo University Hospital, Ullevål, Oslo, Norway.
Rosa BoschInstituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain.
Murielle BrumDepartment of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany.
Ben M BrumptonK. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
Nathalie Brunkhorst-KanaanDepartment of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany.
Monika BuddeInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.
Jonas Bybjerg-GrauholmiPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
William ByerleyPsychiatry, University of California San Francisco, San Francisco, CA, USA.
Judit Cabana-DomínguezInstituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain.
Murray J CairnsSchool of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, New South Wales, Australia.
Bernardo CarpinielloSection of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Miquel CasasPrograma SJD MIND Escoles, Hospital Sant Joan de Déu, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Spain.
Pablo CervantesDepartment of Psychiatry, Mood Disorders Program, McGill University Health Center, Montreal, Québec, Canada.
Chris ChatzinakosDepartment of Psychiatry and Behavioral Sciences, SUNY Downstate Health Sciences University, Brooklyn, NY, USA.
Hsi-Chung ChenDepartment of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan.
Tereza ClarenceDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Toni-Kim ClarkeDivision of Psychiatry, University of Edinburgh, Edinburgh, UK.
Isabelle ClausInstitute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.
Brandon CoombesDepartment of Quantitative Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Elizabeth C CorfieldPsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway.
Cristiana CruceanuDepartment of Psychiatry, Mood Disorders Program, McGill University Health Center, Montreal, Québec, Canada.
Alfredo Cuellar-BarbozaDepartment of Psychiatry, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico.
Piotr M CzerskiDepartment of Psychiatry, Laboratory of Psychiatric Genetics, Poznan University of Medical Sciences, Poznan, Poland.
Konstantinos DafnasNational and Kapodistrian University of Athens, 2nd Department of Psychiatry, Attikon General Hospital, Athens, Greece.
Anders M DaleCenter for Multimodal Imaging and Genetics, Departments of Neurosciences, Radiology, and Psychiatry, University of California, San Diego, CA, USA.
Nina DalknerDivision of Psychiatry and Psychotherapeutic Medicine, Medical University of Graz, Graz, Austria.
Franziska DegenhardtInstitute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.
J Raymond DePauloDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Srdjan DjurovicDepartment of Medical Genetics, Oslo University Hospital Ullevål, Oslo, Norway.
Ole Kristian DrangeCenter for Precision Psychiatry, University of Oslo, Oslo, Norway.
Valentina Escott-PriceCentre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.
Ayman H FanousDepartment of Psychiatry, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USA.
Frederike T FellendorfDivision of Psychiatry and Psychotherapeutic Medicine, Medical University of Graz, Graz, Austria.
I Nicol FerrierAcademic Psychiatry, Newcastle University, Newcastle upon Tyne, UK.
Liz FortyCentre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.
Josef FrankDepartment of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Oleksandr FreiDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Nelson B FreimerCenter for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USA.
John F FullardDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Julie GarnhamDepartment of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.
Ian R GizerDepartment of Psychological Sciences, University of Missouri, Columbia, MO, USA.
Scott D GordonGenetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Katherine Gordon-SmithPsychological Medicine, University of Worcester, Worcester, UK.
Tiffany A GreenwoodDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Jakob GroveiPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
José Guzman-ParraMental Health Department, University Regional Hospital, Biomedicine Institute (IBIMA), Málaga, Spain.
Tae Hyon HaDepartment of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Tim HahnInstitute for Translational Psychiatry, University of Münster, Münster, Germany.
Magnus HaraldssonFaculty of Medicine, Department of Psychiatry, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Martin HautzingerDepartment of Psychology, Eberhard Karls Universität Tübingen, Tubingen, Germany.
Alexandra HavdahlPsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway.
Urs HeilbronnerInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.
Dennis HellgrenDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Stefan HermsInstitute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.
Ian B HickieBrain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia.
Per HoffmannInstitute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.
Peter A HolmansCentre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.
Ming-Chyi HuangDepartment of Psychiatry, Taipei City Psychiatric Center, Taipei City Hospital, Taipei, Taiwan.
Masashi IkedaDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Stéphane JamainUniversité Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, Créteil, France.
Jessica S JohnsonDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Lina JonssonInstitute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.
Janos L KalmanInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.
Yoichiro KamataniLaboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.
James L KennedyCampbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Euitae KimDepartment of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Jaeyoung KimDepartment of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Sarah Kittel-SchneiderDepartment of Psychiatry and Neurobehavioral Science, University College Cork, Cork, Ireland.
James A KnowlesHuman Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ, USA.
Manolis KogevinasISGlobal, Barcelona, Spain.
Thorsten M KranzDepartment of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany.
Kristi KrebsEstonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Steven A KushnerDepartment of Psychiatry, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Catharina LavebrattTranslational Psychiatry, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Jacob LawrencePsychiatry, North East London NHS Foundation Trust, Ilford, UK.
Markus LeberClinic for Psychiatry and Psychotherapy, University Hospital Cologne, Cologne, Germany.
Heon-Jeong LeeDepartment of Psychiatry, Korea University College of Medicine, Seoul, Republic of Korea.
Calwing LiaoAnalytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.
Susanne LucaeDepartment of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.
Martin LundbergTranslational Psychiatry, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Donald J MacIntyreDivision of Psychiatry, Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK.
Wolfgang MaierDepartment of Psychiatry and Psychotherapy, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.
Adam X MaihoferDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Dolores MalaspinaDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Mirko ManchiaSection of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Eirini MaratouNational and Kapodistrian University of Athens, Medical School, Clinical Biochemistry Laboratory, Attikon General Hospital, Athens, Greece.
Lina MartinssonDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Manuel MattheiseniPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
Nathaniel W McGregorHuman and Systems Genetics Working Group, Department of Genetics, Stellenbosch University, Stellenbosch, South Africa.
Melvin G McInnisDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
James D McKayGenetic Cancer Susceptibility Group, International Agency for Research on Cancer, Lyon, France.
Helena MedeirosInstitute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY, USA.
Andreas Meyer-LindenbergDepartment of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Vincent MillischerTranslational Psychiatry, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Derek W MorrisCentre for Neuroimaging and Cognitive Genomics (NICOG), School of Biological and Chemical Sciences, University of Galway, Galway, Ireland.
Paraskevi MoutsatsouNational and Kapodistrian University of Athens, Medical School, Clinical Biochemistry Laboratory, Attikon General Hospital, Athens, Greece.
Thomas W MühleisenDepartment of Biomedicine, University of Basel, Basel, Switzerland.
Claire O'DonovanDepartment of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.
Catherine M OlsenPopulation Health, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Georgia PanagiotaropoulouDepartment of Psychiatry and Psychotherapy, Charité-Universitätsmedizin, Berlin, Germany.
Sergi PapiolInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.
Antonio F PardiñasCentre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.
Hye Youn ParkDepartment of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Amy PerryPsychological Medicine, University of Worcester, Worcester, UK.
Andrea PfennigDepartment of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Claudia PisanuDepartment of Biomedical Sciences, University of Cagliari, Cagliari, Italy.
James B PotashDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Digby QuestedOxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.
Mark H RapaportDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Eline J RegeerOutpatient Clinic for Bipolar Disorder, Altrecht, Utrecht, The Netherlands.
John P RiceDepartment of Psychiatry, Washington University in Saint Louis, Saint Louis, MO, USA.
Margarita RiveraDepartment of Biochemistry and Molecular Biology II, Faculty of Pharmacy, University of Granada, Granada, Spain.
Eva C SchulteInstitute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.
Fanny SennerInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.
Alexey ShadrinDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Paul D ShillingDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Engilbert SigurdssonFaculty of Medicine, Department of Psychiatry, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Lisa SindermannInstitute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.
Lea SirignanoDepartment of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Dan SiskindFaculty of Medicine, University of Queensland, Brisbane, Queensland, Australia.
Claire SlaneyDepartment of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.
Laura G SloofmanDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Olav B SmelandDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Daniel J SmithDivision of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Janet L SobellPsychiatry and the Behavioral Sciences, University of Southern California, Los Angeles, CA, USA.
Maria Soler ArtigasInstituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain.
Dan J SteinSAMRC Unit on Risk and Resilience in Mental Disorders, Dept of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa.
Frederike SteinDepartment of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany.
Mei-Hsin SuVirginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.
Heejong SungHuman Genetics Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD, USA.
Beata ŚwiątkowskaDepartment of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Lodz, Poland.
Chikashi TeraoLaboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Markos TesfayeDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Martin TesliDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Thorgeir E ThorgeirssondeCODE Genetics/Amgen, Reykjavik, Iceland.
Jackson G ThorpMental Health and Neuroscience, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Claudio TomaNeuroscience Research Australia, Sydney, New South Wales, Australia.
Leonardo TondoDepartment of Psychiatry, Harvard Medical School, Boston, MA, USA.
Paul A TooneySchool of Biomedical Science and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.
Shih-Jen TsaiDepartment of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan.
Evangelia Eirini TsermpiniDepartment of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.
Marquis P VawterDepartment of Psychiatry and Human Behavior, School of Medicine, University of California, Irvine, CA, USA.
Helmut VedderPsychiatry, Psychiatrisches Zentrum Nordbaden, Wiesloch, Germany.
Annabel VreekerPsychiatry, Brain Center UMC Utrecht, Utrecht, The Netherlands.
James T R WaltersCentre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.
Bendik S WinsvoldHUNT Center for Molecular and Clinical Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
Stephanie H WittDepartment of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Hong-Hee WonSamsung Advanced Institute for Health Sciences and Technology (SAIHST), Sungkyunkwan University, Samsung Medical Center, Seoul, Republic of Korea.
Robert YeAnalytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.
Allan H YoungDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Peter P ZandiDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Lea ZillichDepartment of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
23andMe Research Team
Rolf AdolfssonDepartment of Clinical Sciences, Psychiatry, Umeå University Medical Faculty, Umeå, Sweden.
Martin AldaDepartment of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.
Lars AlfredssonInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Lena BacklundTranslational Psychiatry, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Bernhard T BauneDepartment of Psychiatry, University of Münster, Münster, Germany.
Frank BellivierUniversité Paris Cité, INSERM, Optimisation Thérapeutique en Neuropsychopharmacologie, UMRS-1144, Paris, France.
Susanne BengesserDivision of Psychiatry and Psychotherapeutic Medicine, Medical University of Graz, Graz, Austria.
Wade H BerrettiniPsychiatry, University of Pennsylvania, Philadelphia, PA, USA.
Joanna M BiernackaDepartment of Quantitative Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Michael BoehnkeCenter for Statistical Genetics and Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.
Anders D BørglumiPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
Gerome BreenSocial, Genetic and Developmental Psychiatry Centre, King's College London, London, UK.
Vaughan J CarrDiscipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia.
Stanley CattsUniversity of Queensland, Brisbane, Queensland, Australia.
Sven CichonInstitute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.
Aiden CorvinNeuropsychiatric Genetics Research Group, Department of Psychiatry and Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland.
Nicholas CraddockCentre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.
Udo DannlowskiInstitute for Translational Psychiatry, University of Münster, Münster, Germany.
Dimitris DikeosNational and Kapodistrian University of Athens, 1st Department of Psychiatry, Eginition Hospital, Athens, Greece.
Bruno EtainUniversité Paris Cité, INSERM, Optimisation Thérapeutique en Neuropsychopharmacologie, UMRS-1144, Paris, France.
Panagiotis FerentinosSocial, Genetic and Developmental Psychiatry Centre, King's College London, London, UK.
Mark FryeDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.
Janice M FullertonNeuroscience Research Australia, Sydney, New South Wales, Australia.
Micha GawlikDepartment of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital Würzburg, Würzburg, Germany.
Elliot S GershonDepartment of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA.
Fernando S GoesDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Melissa J GreenNeuroscience Research Australia, Sydney, New South Wales, Australia.
Maria Grigoroiu-SerbanescuBiometric Psychiatric Genetics Research Unit, Alexandru Obregia Clinical Psychiatric Hospital, Bucharest, Romania.
Joanna HauserDepartment of Psychiatric Genetics, Poznan University of Medical Sciences, Poznan, Poland.
Frans A HenskensSchool of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia.
Jens Hjerling-LefflerDepartment of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
David M HougaardiPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
Kristian HveemK. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
Nakao IwataDepartment of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan.
Ian JonesCentre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.
Lisa A JonesPsychological Medicine, University of Worcester, Worcester, UK.
René S KahnDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
John R KelsoeDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Tilo KircherDepartment of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany.
George KirovCentre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.
Po-Hsiu KuoDepartment of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan.
Mikael LandénDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Marion LeboyerUniversité Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, Créteil, France.
Qingqin S LiNeuroscience Therapeutic Area, Janssen Research and Development, Titusville, NJ, USA.
Jolanta LissowskaCancer Epidemiology and Prevention, M. Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
Christine LochnerSA MRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry, Stellenbosch University, Stellenbosch, South Africa.
Carmel LoughlandUniversity of Newcastle, Newcastle, New South Wales, Australia.
Jurjen J LuykxDepartment of Psychiatry, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Nicholas G MartinGenetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Carol A MathewsDepartment of Psychiatry, University of Florida, Gainesville, FL, USA.
Fermin MayoralMental Health Department, University Regional Hospital, Biomedicine Institute (IBIMA), Málaga, Spain.
Susan L McElroyResearch Institute, Lindner Center of HOPE, Mason, OH, USA.
Andrew M McIntoshDivision of Psychiatry, Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK.
Francis J McMahonHuman Genetics Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD, USA.
Sarah E MedlandMental Health and Neuroscience, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Ingrid MelleDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Lili MilaniEstonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Philip B MitchellDiscipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia.
Gunnar MorkenDepartment of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
Ole MorsiPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
Preben Bo MortenseniPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
Bertram Müller-MyhsokDepartment of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.
Richard M MyersHudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.
Woojae MyungDepartment of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Benjamin M NealeAnalytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.
Caroline M NievergeltDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Merete NordentoftiPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
Markus M NöthenInstitute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.
John I NurnbergerPsychiatry, Indiana University School of Medicine, Indianapolis, IN, USA.
Michael C O'DonovanCentre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.
Ketil J OedegaardDivision of Psychiatry, Haukeland Universitetssjukehus, Bergen, Norway.
Tomas OlssonDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Michael J OwenCentre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.
Sara A PacigaHuman Genetics and Computational Biomedicine, Pfizer Global Research and Development, Groton, CT, USA.
Christos PantelisThe Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia.
Carlos N PatoRutgers Health, Rutgers University, Piscataway, NJ, USA.
Michele T PatoRutgers Health, Rutgers University, Piscataway, NJ, USA.
George P PatrinosUniversity of Patras, School of Health Sciences, Department of Pharmacy, Laboratory of Pharmacogenomics and Individualized Therapy, Patras, Greece.
Joanna M PawlakDepartment of Psychiatric Genetics, Poznan University of Medical Sciences, Poznan, Poland.
Josep Antoni Ramos-QuirogaInstituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain.
Andreas ReifDepartment of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany.
Eva Z ReininghausDivision of Psychiatry and Psychotherapeutic Medicine, Medical University of Graz, Graz, Austria.
Marta RibasésInstituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain.
Marcella RietschelDepartment of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Stephan RipkeAnalytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.
Guy A RouleauDepartment of Neurology and Neurosurgery, Faculty of Medicine, McGill University, Montreal, Québec, Canada.
Panos RoussosDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Takeo SaitoDepartment of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan.
Ulrich SchallCentre for Brain and Mental Health Research, The University of Newcastle, Newcastle, New South Wales, Australia.
Martin SchallingTranslational Psychiatry, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Peter R SchofieldNeuroscience Research Australia, Sydney, New South Wales, Australia.
Thomas G SchulzeInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.
Laura J ScottCenter for Statistical Genetics and Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.
Rodney J ScottThe School of Biomedical Sciences and Pharmacy, Faculty of Medicine, Health and Wellbeing, University of Newcastle, Newcastle, New South Wales, Australia.
Alessandro SerrettiDepartment of Medicine and Surgery, Kore University of Enna, Enna, Italy.
Jordan W SmollerStanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA.
Alessio SquassinaDepartment of Biomedical Sciences, University of Cagliari, Cagliari, Italy.
Eli A StahlDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Hreinn StefanssondeCODE Genetics/Amgen, Reykjavik, Iceland.
Kari StefanssondeCODE Genetics/Amgen, Reykjavik, Iceland.
Eystein StordalDepartment of Psychiatry, Hospital Namsos, Namsos, Norway.
Fabian StreitDepartment of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Patrick F SullivanDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Gustavo TureckiDepartment of Psychiatry, McGill University, Montreal, Québec, Canada.
Arne E VaalerDepartment of Psychiatry, Sankt Olavs Hospital Universitetssykehuset i Trondheim, Trondheim, Norway.
Eduard VietaClinical Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain.
John B VincentCampbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Irwin D WaldmanDepartment of Psychology, Emory University, Atlanta, GA, USA.
Cynthia S WeickertNeuroscience Research Australia, Sydney, New South Wales, Australia.
Thomas W WeickertNeuroscience Research Australia, Sydney, New South Wales, Australia.
Thomas WergeiPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
David C WhitemanPopulation Health, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
John-Anker ZwartInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Howard J EdenbergBiochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA.
Andrew McQuillinDivision of Psychiatry, University College London, London, UK.
Andreas J ForstnerInstitute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.
Niamh MullinsDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Arianna Di FlorioCentre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.
Roel A OphoffDepartment of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Ole A AndreassenDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway. ole.andreassen@medisin.uio.no.ORCID http://orcid.org/0000-0002-4461-3568
Bipolar Disorder Working Group of the Psychiatric Genomics Consortium
Funding
1/7 Psychiatric Genomics Consortium: Finding actionable variationU01MH109528 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SULLIVAN, PATRICK F · 2016 to 2020
$2.5M3/7 Psychiatric Genomics Consortium: Advancing Discovery and ImpactR01MH124839 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ANDREASSEN, OLE A, HUCKINS, LAURA MARIANNE · 2021 to 2025
$2.0M1/4 Psychiatric GWAS Consortium: Genomic Follow-up Next-Gen Sequencing & GenotypiU01MH094421 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SULLIVAN, PATRICK F · 2012 to 2015
$1.9M1/5-The Psychiatric GWAS Consortium: Integrated & Coordinated GWAS Meta-AnalysesU01MH085520 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SULLIVAN, PATRICK F · 2008 to 2008
$642kNIMH NIH HHS R01 MH124839NIMH NIH HHS U01 MH085520NIMH NIH HHS U01 MH094421NIMH NIH HHS U01 MH109528World Health Organization 001
Abstract
Bipolar disorder is a leading contributor to the global burden of disease
Indexed as
Bipolar DisorderGenomicsBlack or African AmericanChromosome MappingCohort StudiesFemaleGenetic Predisposition to DiseaseGenome-Wide Association StudyHispanic or LatinoHumansMalePhenotypeWhiteWhite People
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.