ArticleNature2025
Tissue-resident memory CD8 T cell diversity is spatiotemporally imprinted.
Abstract read
In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
67 citing papers in PubMed.
- Barrier immune memory is programmed by intestinal epithelial cell presentation of cytosol-delivered bacterial antigens.Nature immunology · 2026Article
- Multiplatform single-cell and spatial transcriptomics reveal sex-specific malignant states and architecture in male breast cancer.Science advances · 2026Article
- Article
- A spatial and temporal transcriptomic atlas of mouse intestinal regeneration in the jejunum.Nature communications · 2026Article
- Bacterial mRNA Vaccines: Programming Immunity Against Antimicrobial Resistance.Drug development research · 2026Review
- Pregnancy-induced tissue-resident memory-like T cells contribute to tumor control in breast cancer.Nature immunology · 2026Article
- Epithelial-Dermal Immune Memory: TrackingInternational journal of molecular sciences · 2026Review
- GZMK-expressing tissue-resident memory CD8+ T cells participate in human intestinal acute graft-versus-host disease.JCI insight · 2026Article
- Identifying a Csmd3Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Trimodal, uncertainty-guided whole-slide framework for genome-scale spatial expression and image-only virtual perturbation in cancer cohorts.Genome medicine · 2026Article
- Harnessing mucosal immunity for protective vaccines.Nature reviews. Immunology · 2026Review
- A spatial transit-retention axis reveals adaptive immune organisation in psoriatic disease.Molecular and cellular biochemistry · 2026Article
- CD8MedComm · 2026Review
- Spatial Immunology in Translation: Linking Immune Organisation to Therapeutic Outcome.Medical sciences (Basel, Switzerland) · 2026Review
- Article
- AI-driven big data analysis and predictive modeling of infectious disease immunity: from correlates to causal, multiscale understanding.Archives of microbiology · 2026Review
- Article
- Cross-reactive tissue-resident memory T lymphocytes-concepts, evidence, and open questions.Journal of translational medicine · 2026Review
- CD163 and Tim-4 identify resident intestinal macrophages that are spatially regulated by TGF-β.The Journal of experimental medicine · 2026Article
- Coincident epithelial signals restrain commensal-specific CD8αβbioRxiv : the preprint server for biology · 2026Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
- Update of
Authors and funding
20 authors.
Miguel Reina-Campos *School of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.
Alexander Monell *School of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0002-5399-2205
Amir FerrySchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0003-2884-083X
Vida LunaSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0002-6300-8128
Kitty P CheungSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.
Giovanni GallettiSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0001-6613-2354
Nicole E ScharpingSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.
Kennidy K TakeharaSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.
Sara QuonSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0003-3860-3491
Peter P ChallitaSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.ORCID 0009-0004-8634-031X
Brigid BolandDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.
Yun Hsuan LinDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID 0009-0008-5997-9109
William H WongDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.
Cynthia S IndralingamDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.
Hayley NeadeauLa Jolla Institute for Immunology, La Jolla, CA, USA.ORCID 0009-0004-5011-5989
Suzie AlarcónLa Jolla Institute for Immunology, La Jolla, CA, USA.
Gene W YeoDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0002-0799-6037
John T ChangDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0003-0873-6218
Maximilian Heeg *School of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA, USA. maximilian.heeg@alleninstitute.org.ORCID 0000-0002-9594-1377
Ananda W GoldrathSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA, USA. agoldrath@alleninstitute.org.ORCID 0000-0002-5900-508X
Funding
San Diego Digestive Diseases Research CenterP30DK120515 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Bernd G. Schnabl · 2019 to 2026
$10.8MSingle-Cell Transcriptomic and Epigenetics CoreP01AI132122 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ZUNIGA, ELINA I · 2018 to 2022
$9.8MU of Calif, San Diego Neuroscience Microscopy ImagingP30NS047101 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GLEESON, JOSEPH G, ZHENG, BINHAI · 2003 to 2022
$9.0MRegulation of T cell immunity to viral infectionR01AI072117 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GOLDRATH, ANANDA W · 2008 to 2022
$5.4MSystems-level identification of key regulators deciding immune cell stateR01AI150282 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WANG, WEI · 2020 to 2024
$3.5MT cell maintenance: molecular mediators of T cell differentiation and survivalR37AI067545 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ananda W Goldrath · 2022 to 2026
$3.0MTissue-specific adaptions to promote localized T cell memoryR01AI179952 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ananda W Goldrath · 2024 to 2026
$1.8MDissecting stress granule dependencies in leukemia stem cellsR01CA273432 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI John T Chang, Eugene Wei-Ming Yeo · 2023 to 2026
$1.8MNovaSeq5000 High Throughput SequencerS10OD025052 · OD · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI SEUMOIS, GREGORY · 2018 to 2018
$832kTumor-infiltrating T cell metabolic dysfunction and genetic reprogramming for effective immunotherapyK00CA222711 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SCHARPING, NICOLE E · 2020 to 2023
$360kUnderstanding Prostate Resident Memory T CellsF31AI176705 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TAKEHARA, KENNIDY · 2024 to 2025
$64kCSRD VA I01 CX002396NCI NIH HHS K00 CA222711NCI NIH HHS R01 CA273432NIAID NIH HHS F31 AI176705NIAID NIH HHS P01 AI132122NIAID NIH HHS R01 AI072117NIAID NIH HHS R01 AI150282NIAID NIH HHS R01 AI179952NIAID NIH HHS R37 AI067545NIDDK NIH HHS P30 DK120515NIH HHS S10 OD025052NINDS NIH HHS P30 NS047101
Abstract
Tissue-resident memory CD8 T (T
Indexed as
CD8-Positive T-LymphocytesImmunologic MemoryIntestine, SmallMemory T CellsAnimalsCell DifferentiationChemokine CXCL10FemaleHumansMaleMiceMice, Inbred C57BLTranscriptomeTransforming Growth Factor betaChemokine CXCL10Transforming Growth Factor beta
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.