Evidence map›Paper›PMID 39843747›Full record

ArticleNature2025

A map of the rubisco biochemical landscape.

Noam Prywes, Naiya R Phillips, Luke M Oltrogge, Sebastian Lindner, Leah J Taylor-Kearney, Yi-Chin Candace Tsai, Benoit de Pins, Aidan E Cowan, Hana A Chang, Renée Z Wang and 11 more

Erratum issuedAbstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Semiartificial COChemical reviews · 2026
    Review
  7. Article
  8. Review
  9. Achieving High-Density and Stress-Resilient Maize Breeding Via Germplasm Innovation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. RuBisCO-based COFrontiers in bioengineering and biotechnology · 2026
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Noam PrywesInnovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA.ORCID 0000-0003-2526-2392
Naiya R PhillipsDepartment of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA.ORCID 0000-0003-1836-5182
Luke M OltroggeHoward Hughes Medical Institute, University of California Berkeley, Berkeley, CA, USA.ORCID 0000-0001-5716-9980
Sebastian LindnerUniversity of Heidelberg, Heidelberg, Germany.ORCID 0009-0009-8251-2758
Leah J Taylor-KearneyDepartment of Plant and Microbial Biology, University of California Berkeley, Berkeley, CA, USA.ORCID 0000-0001-7530-7670
Yi-Chin Candace TsaiSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Benoit de PinsDepartment of Biology, University of Naples Federico II, Naples, Italy.
Aidan E CowanDepartment of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA.
Hana A ChangDepartment of Plant and Microbial Biology, University of California Berkeley, Berkeley, CA, USA.ORCID 0009-0005-1919-0363
Renée Z WangDepartment of Plant and Microbial Biology, University of California Berkeley, Berkeley, CA, USA.ORCID 0000-0003-3994-3244
Laina N HallBiophysics, University of California Berkeley, Berkeley, CA, USA.ORCID 0000-0003-3135-332X
Daniel Bellieny-RabeloInnovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA.ORCID 0000-0003-2544-7899
Hunter M NisonoffCenter for Computational Biology, University of California Berkeley, Berkeley, CA, USA.ORCID 0000-0003-1357-8111
Rachel F WeissmanDepartment of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA.
Avi I FlamholzDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
David DingInnovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA.
Abhishek Y BhattDepartment of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA.
Oliver Mueller-CajarSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.ORCID 0000-0003-2866-5963
Patrick M ShihInnovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA.ORCID 0000-0002-2119-3345
Ron MiloDepartment of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, Israel.
David F SavageInnovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA. savage@berkeley.edu.ORCID 0000-0003-0042-2257

Funding

Synthetic biology and organelle genomics: A rubisco library as a case study in evolutionary landscapes and organellar engineeringK99GM141455 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI PRYWES, NOAM · 2021 to 2022
$188k
NIGMS NIH HHS K99 GM141455
6 · The paper itself

Abstract

Rubisco is the primary CO

Indexed as

Escherichia coliRibulose-Bisphosphate CarboxylaseAmino Acid SubstitutionCarbon DioxideConserved SequenceKineticsModels, MolecularMutationProtein EngineeringCarbon DioxideRibulose-Bisphosphate Carboxylase

Identifiers

PMID39843747
PMCPMC11839469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.