Evidence map›Paper›PMID 39843743›Full record

ArticleNature2025

Resolving native GABA

Jia Zhou, Colleen M Noviello, Jinfeng Teng, Haley Moore, Bradley Lega, Ryan E Hibbs

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Temperature and intrinsic CaNature structural & molecular biology · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Molecular assemblies and pharmacology of cerebellar GABAProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Efficient and rapid isolation of native AMPA receptor complexes for cryo-EM.Protein science : a publication of the Protein Society · 2026
    Article
  10. Article
  11. Direct modulation of human GABA-A αFrontiers in neuroscience · 2026
    Review
  12. Article
  13. Review
  14. GABAFrontiers in immunology · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jia ZhouDepartment of Neurobiology, University of California San Diego, La Jolla, CA, USA.
Colleen M NovielloDepartment of Neurobiology, University of California San Diego, La Jolla, CA, USA.
Jinfeng TengDepartment of Neurobiology, University of California San Diego, La Jolla, CA, USA.
Haley MooreDepartment of Neuroscience, UT Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0002-4562-6774
Bradley LegaDepartments of Neurological Surgery, Neurology, Psychiatry and the Peter O'Donnell Jr. Brain Institute, UT Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0003-3634-406X
Ryan E HibbsDepartment of Neurobiology, University of California San Diego, La Jolla, CA, USA. rehibbs@ucsd.edu.ORCID 0000-0003-4283-1147

Funding

Structure and Function of GABA-A ReceptorsR01DA047325 · NIDA · UT SOUTHWESTERN MEDICAL CENTER · PI Ryan E Hibbs, David W Nauen · 2019 to 2026
$4.4M
Deciphering the genomic mechanisms underlying the physiology of human brain stimulationRF1NS126143 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI KONOPKA, GENEVIEVE, LEGA, BRADLEY C · 2022 to 2024
$4.0M
The role of SMAD3 in gene networks underlying human brain activityF31NS132443 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI MOORE, HALEY D · 2024 to 2025
$80k
American Heart AssociationNIDA NIH HHS R01 DA047325NINDS NIH HHS F31 NS132443NINDS NIH HHS RF1 NS126143
6 · The paper itself

Abstract

Type A GABA (γ-aminobutyric acid) receptors (GABA

Indexed as

BrainCryoelectron MicroscopyReceptors, GABA-AAnimalsAnticonvulsantsBenzodiazepinesBinding SitesEpilepsyFemaleHumansMaleMembrane ProteinsModels, MolecularNerve Tissue ProteinsProtein SubunitsProteomicsAnticonvulsantsBenzodiazepinesMembrane ProteinsNerve Tissue ProteinsProtein SubunitsReceptors, GABA-A

Identifiers

PMID39843743
PMCPMC12103249

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.