Evidence map›Paper›PMID 39843604›Full record

ArticleScientific reports2025

Effects of key physiological parameters on cardiovascular disease and osteoporosis risk in perimenopausal and postmenopausal women.

Hong Mou, Jun Zhang, Yichuan Guo, Liangzhi Xu, Xiaoyan Luo

Erratum issuedAbstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Menopause matters: A community-based cross-sectional online survey among midlife women in Malaysia.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2026
    Article
  10. Article
  11. Article
  12. Improvement of Menopausal Symptoms byFood science & nutrition · 2025
    Article
  13. Fibromyalgia: Chronic Pain Due to a Blood Dysfunction?International journal of molecular sciences · 2025
    Review
  14. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Hong MouDepartment of Medical Genetics/Prenatal Diagnostic Center, West China Second University Hospital, Sichuan University, Chengdu, China.
Jun ZhangDepartment of Obstetrics, People's Hospital of Xishuangbanna Dai Autonomous Prefecture, Jinghong, China.
Yichuan GuoKey Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu, P.R. China.
Liangzhi XuKey Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu, P.R. China. liangzxu@126.com.
Xiaoyan LuoKey Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu, P.R. China. luoxiaoyan0917@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The essential cause of menopause is ovarian failure, which can cause decline in sex hormones (especially estrogen) that can increase the risk of metabolic diseases, such as cardiovascular disease and osteoporosis. This study screened 1511 eligible patients from 2148 perimenopausal and postmenopausal women, measuring various physiological and biochemical indicators to analyze differences among age groups (40-44, 45-49, and 50-54 years) with laboratory techniques. The study found no significant difference in the incidence of cardiovascular disease betweenperimenopausal and postmenopausal women. But the incidence of osteoporosis was higher in postmenopausal women and was associated with age (p < 0.05). Additionally, follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E

Indexed as

Cardiovascular DiseasesOsteoporosisOsteoporosis, PostmenopausalPerimenopausePostmenopauseAdultBone DensityEstradiolFemaleFollicle Stimulating HormoneHumansIncidenceLuteinizing HormoneMiddle AgedRisk FactorsEstradiolFollicle Stimulating HormoneLuteinizing HormoneCardiovascular diseaseEstradiolOsteoporosisPerimenopausalPostmenopausal

Identifiers

PMID39843604
PMCPMC11754902

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.