Evidence map›Paper›PMID 39843580›Full record

ArticleNature biotechnology2025

A platform for the biomedical application of large language models.

Sebastian Lobentanzer, Shaohong Feng, Noah Bruderer, Andreas Maier, BioChatter Consortium, Cankun Wang, Jan Baumbach, Jorge Abreu-Vicente, Nils Krehl, Qin Ma and 2 more

Abstract readLetter
In one paragraph

Article in Nature biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  16. Epistemic compression in large language model explanations of the gut-liver axis.Frontiers in cellular and infection microbiology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sebastian LobentanzerHeidelberg University, Faculty of Medicine and Heidelberg University Hospital, Institute for Computational Biomedicine, Heidelberg, Germany. sebastian.lobentanzer@gmail.com.ORCID http://orcid.org/0000-0003-3399-6695
Shaohong FengDepartment of Biomedical Informatics, The Ohio State University, Columbus, OH, USA.
Noah BrudererMichael Sars Centre, University of Bergen, Bergen, Norway.ORCID http://orcid.org/0009-0003-0551-2435
Andreas MaierInstitute for Computational Systems Biology, University of Hamburg, Hamburg, Germany.ORCID http://orcid.org/0000-0003-4408-0068
BioChatter Consortium
Cankun WangDepartment of Biomedical Informatics, The Ohio State University, Columbus, OH, USA.
Jan BaumbachInstitute for Computational Systems Biology, University of Hamburg, Hamburg, Germany.ORCID http://orcid.org/0000-0002-0282-0462
Jorge Abreu-VicenteEMBO, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-0211-6416
Nils KrehlHeidelberg University, Faculty of Medicine and Heidelberg University Hospital, Institute for Computational Biomedicine, Heidelberg, Germany.ORCID http://orcid.org/0009-0003-1780-6123
Qin MaDepartment of Biomedical Informatics, The Ohio State University, Columbus, OH, USA.ORCID http://orcid.org/0000-0002-3264-8392
Thomas LembergerEMBO, Heidelberg, Germany.
Julio Saez-RodriguezHeidelberg University, Faculty of Medicine and Heidelberg University Hospital, Institute for Computational Biomedicine, Heidelberg, Germany. saezlab@ebi.ac.uk.ORCID http://orcid.org/0000-0002-8552-8976

Funding

TriState SenNET (Lung and Heart) Tissue Map and Atlas consortiumU54AG075931 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TOREN FINKEL, Melanie Koenigshoff · 2021 to 2026
$14.0M
SCH: Graph-based Spatial Transcriptomics Computational Methods in Kidney DiseasesR01DK138504 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Michael Thomas Eadon, Qin Ma · 2023 to 2026
$1.1M
EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 101057619EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 965193Foundation for the National Institutes of Health (Foundation for the National Institutes of Health, Inc.) R01DK138504Foundation for the National Institutes of Health (Foundation for the National Institutes of Health, Inc.) U54AG075931NIA NIH HHS U54 AG075931NIDDK NIH HHS R01 DK138504
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39843580
PMCPMC12216031

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.