Evidence map›Paper›PMID 39843417›Full record

ArticleVirulence2025

Lactic acid in the vaginal milieu modulates the

Diletta Rosati, Marisa Valentine, Mariolina Bruno, Arnab Pradhan, Axel Dietschmann, Martin Jaeger, Ian Leaves, Frank L van de Veerdonk, Leo A B Joosten, Sumita Roy and 6 more

Abstract read
In one paragraph

Article in Virulence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. State-of-the-Art Review: Managing Vulvovaginal Candidiasis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Review
  6. Article
  7. Probiotic and Postbiotic Interactions ofAntibiotics (Basel, Switzerland) · 2026
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Diletta RosatiDepartment of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, T he Netherlands.ORCID 0000-0003-2992-2503
Marisa ValentineDepartment of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute, Jena, Germany.
Mariolina BrunoDepartment of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, T he Netherlands.
Arnab PradhanMedical Research Council Centre for Medical Mycology, University of Exeter, Exeter, UK.
Axel DietschmannJunior Research Group Adaptive Pathogenicity Strategies, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute, Jena, Germany.
Martin JaegerDepartment of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, T he Netherlands.
Ian LeavesMedical Research Council Centre for Medical Mycology, University of Exeter, Exeter, UK.
Frank L van de VeerdonkDepartment of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, T he Netherlands.
Leo A B JoostenDepartment of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, T he Netherlands.
Sumita RoyMedical Research Council Centre for Medical Mycology, University of Exeter, Exeter, UK.
Mark H T StappersMedical Research Council Centre for Medical Mycology, University of Exeter, Exeter, UK.
Neil A R GowMedical Research Council Centre for Medical Mycology, University of Exeter, Exeter, UK.
Bernhard HubeDepartment of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute, Jena, Germany.
Alistair J P BrownMedical Research Council Centre for Medical Mycology, University of Exeter, Exeter, UK.
Mark S GresnigtJunior Research Group Adaptive Pathogenicity Strategies, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute, Jena, Germany.
Mihai G NeteaDepartment of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, T he Netherlands.

Funding

Wellcome TrustWellcome Trust 101873/Z/13/ZWellcome Trust 200208/A/15/ZWellcome Trust 215599/Z/19/ZWellcome Trust 224323/Z/21/Z
6 · The paper itself

Abstract

Vulvovaginal candidiasis (VVC) is one of the most common infections caused by

Indexed as

Candida albicansCandidiasis, VulvovaginalHost-Pathogen InteractionsLactic AcidVaginaCell WallEpithelial CellsFemaleHumansHyphaeNeutrophilsLactic Acidcandida albicanshost responselactic acidvaginal simulative mediumVulvovaginal candidiasis

Identifiers

PMID39843417
PMCPMC11760238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.