Evidence map›Paper›PMID 39843390›Full record

ArticleJournal of the American Society for Mass Spectrometry2025

Locating Polyubiquitin Receptors on the 19S Regulatory Proteasome of

Yiran Ma, Bingqing Zhao, Amit K S Gautam, Caroline Davis, Jonathan C Trinidad, James P Reilly, David E Clemmer, Andreas Matouschek

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yiran MaDepartment of Chemistry, Indiana University, Bloomington, Indiana 47405, United States.
Bingqing ZhaoDepartment of Chemistry, Indiana University, Bloomington, Indiana 47405, United States.
Amit K S GautamDepartment of Molecular Biosciences, University of Texas, Austin, Texas 78712, United States.
Caroline DavisDepartment of Molecular Biosciences, University of Texas, Austin, Texas 78712, United States.ORCID 0000-0002-6765-7491
Jonathan C TrinidadDepartment of Chemistry, Indiana University, Bloomington, Indiana 47405, United States.
James P ReillyDepartment of Chemistry, Indiana University, Bloomington, Indiana 47405, United States.ORCID 0000-0002-9784-1804
David E ClemmerDepartment of Chemistry, Indiana University, Bloomington, Indiana 47405, United States.ORCID 0000-0003-4039-1360
Andreas MatouschekDepartment of Molecular Biosciences, University of Texas, Austin, Texas 78712, United States.ORCID 0000-0001-6016-2341

Funding

Characterizing proteasome-substrate interactions by mass spectrometry proteomicsR01GM135264 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI CLEMMER, DAVID E., MATOUSCHEK, ANDREAS · 2020 to 2024
$1.4M
NIGMS NIH HHS R01 GM135264
6 · The paper itself

Abstract

The effectiveness of state-of-the-art cross-linking strategies and mass spectrometry (MS) detection was explored in an important biological context, namely, the ubiquitin-proteasome system, which is responsible for most of the regulated protein degradation in eukaryotic cells. The locations of possible binding sites on the

Indexed as

Cross-Linking ReagentsMass SpectrometryPolyubiquitinProteasome Endopeptidase ComplexSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsBinding SitesProtein BindingSuccinimidesbis(sulfosuccinimidyl)suberateCross-Linking ReagentsPolyubiquitinProteasome Endopeptidase ComplexSaccharomyces cerevisiae ProteinsSuccinimides

Identifiers

PMID39843390
PMCPMC13592084

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.