Evidence map›Paper›PMID 39842899›Full record

ArticleBMJ case reports2025

Chronic pulmonary silicone embolism after breast implant rupture: an underdiagnosed cause of acute fibrinous and organizing pneumonia?

Catia Vieira Gomes, Nicolas Coquoz, Jeanne Vervier, Stephane Yerly, Pierre-Olivier Bridevaux

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Catia Vieira GomesPneumology, Centre Hospitalier du Valais Romand, Sion, Switzerland catia.gomes@hotmail.ch.ORCID http://orcid.org/0009-0003-5306-0402
Nicolas CoquozPneumology, Centre Hospitalier du Valais Romand, Sion, Switzerland.
Jeanne VervierPneumology, Centre Hospitalier du Valais Romand, Sion, Switzerland.
Stephane YerlyPathology, Centre Hospitalier du Valais Romand, Sion, Valais, Switzerland.
Pierre-Olivier BridevauxPneumology, Centre Hospitalier du Valais Romand, Sion, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A woman in her mid-70s presented with worsening dyspnoea, cough and fatigue initially treated for pneumonia. Despite antibiotics, her condition deteriorated, prompting further investigation. Medical history included previous breast implants, the latter of which had ruptured years earlier and was subsequently removed prior to the current presentation. Imaging revealed bilateral lung consolidations and lymphadenopathy. Bronchoalveolar lavage indicated macrophagic alveolitis, while biopsies showed chronic inflammation and the presence of silicone. Diagnosis of chronic pulmonary silicone embolism was made, a rare condition linked to the migration of silicone particles into the lungs, causing inflammation. Treatment involved corticosteroids, leading to symptom resolution. This case highlights the diagnostic challenges of silicone pneumonitis, which can manifest years after implant rupture and removal. Clinicians should be aware of this condition to avoid misdiagnosis and delayed treatment, as symptoms may persist even after implant removal due to irreversible lung fibrosis.

Indexed as

Breast ImplantsCryptogenic Organizing PneumoniaPneumoniaPulmonary EmbolismSiliconesAgedChronic DiseaseDevice RemovalDiagnosis, DifferentialFemaleHumansOrganizing PneumoniaProsthesis FailureSiliconesGlobal HealthInterstitial lung disease

Identifiers

PMID39842899
PMCPMC11795241

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.