Evidence map›Paper›PMID 39842819›Full record

ArticleRenal failure2025

The effect of low donor-to-recipient body weight ratio on graft survival after dual kidney transplantation from pediatric deceased donors.

Mingchuan Huang, Shenghui Wu, Pengfei Gao, Li Zhou, Qian Fu, Chenglin Wu, Huanxi Zhang, Yitao Zheng, Xiaojun Su, Wenrui Wu and 7 more

Abstract read
In one paragraph

Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Pediatric Kidney Transplantation: A Systematic Review.Children (Basel, Switzerland) · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Mingchuan HuangDepartment of Pediatric Surgery, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Shenghui WuFirst Affiliated Hospital, Nanjing Medical University, Nanjing, China.
Pengfei GaoDepartment of Pediatric Surgery, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Li ZhouDepartment of Pediatric Surgery, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Qian FuOrgan Transplantation Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Chenglin WuOrgan Transplantation Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Huanxi ZhangOrgan Transplantation Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yitao ZhengKidney Transplantation Department, The Third People's Hospital of Shenzhen, Shenzhen, China.
Xiaojun SuOrgan Transplantation Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Wenrui WuOrgan Transplantation Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Jinghong TanOrgan Transplantation Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Qiang ZhangOrgan Transplantation Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Pei XiaDepartment of Pathology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Zhe XuDepartment of Pediatric Surgery, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Longshan LiuOrgan Transplantation Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Jun LiOrgan Transplantation Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Changxi WangOrgan Transplantation Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDual kidney transplantation (DKT) from small pediatric donors, either en-bloc or split dual kidney transplantation, contributes to mitigating organ scarcity. This study investigates the prognosis of DKT from pediatric deceased donors, and influencing factors.

methodA retrospective study included recipients who underwent DKT from pediatric donors between 2012 and 2022. Recipients were categorized into low mismatch (BWLM,

resultForty recipients were included. The average follow-up period was 54.6 months. The 1, 3, and 5-year patient survival were 97.4%, with no significant differences between en-bloc and split dual kidney transplantation or between BWLM and BWHM groups. The graft survival at 1, 3, and 5 years were 89.9%, the graft survival of BWHM group was lower than BWLM group (70% vs 96.7%,

conclusionDKT from pediatric donors yields favorable outcomes, with similar graft survival and complication rates across surgical subgroups. However, significant donor-recipient weight mismatch, particularly when the ratio is less than 1:10, may contribute to increased surgical complications and poorer graft survival. Efforts to minimize extreme weight mismatch are recommended to optimize outcomes.

Indexed as

Body WeightGraft SurvivalKidney Failure, ChronicKidney TransplantationTissue DonorsAdolescentAdultChildChild, PreschoolFemaleGlomerular Filtration RateHumansMaleRetrospective Studiesbody weight ratioDual kidney transplantpediatric donorsurgical proceduresurvival analysis

Identifiers

PMID39842819
PMCPMC11755734

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.