Evidence map›Paper›PMID 39842794›Full record

ArticleEndocrine journal2025

Long-term outcomes after a radioactive iodine treatment for a single autonomous functioning thyroid nodule in Japan.

Ai Yoshihara, Jaeduk Yoshimura Noh, Kosuke Inoue, Masakazu Koshibu, Rei Hirose, Masahiro Ichikawa, Nami Suzuki, Masako Matsumoto, Miho Fukushita, Natsuko Watanabe and 2 more

Abstract read
In one paragraph

Article in Endocrine journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ai YoshiharaDepartment of Internal Medicine, Ito Hospital, Tokyo 150-8308, Japan.ORCID http://orcid.org/0000-0003-1323-4722
Jaeduk Yoshimura NohDepartment of Internal Medicine, Ito Hospital, Tokyo 150-8308, Japan.ORCID http://orcid.org/0000-0001-7340-8603
Kosuke InoueDepartment of Social Epidemiology, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.ORCID http://orcid.org/0000-0001-9614-8103
Masakazu KoshibuDepartment of Internal Medicine, Ito Hospital, Tokyo 150-8308, Japan.ORCID http://orcid.org/0009-0007-0170-2804
Rei HiroseDepartment of Internal Medicine, Ito Hospital, Tokyo 150-8308, Japan.ORCID http://orcid.org/0009-0006-2998-7656
Masahiro IchikawaDepartment of Internal Medicine, Ito Hospital, Tokyo 150-8308, Japan.ORCID http://orcid.org/0000-0002-6594-5342
Nami SuzukiDepartment of Internal Medicine, Ito Hospital, Tokyo 150-8308, Japan.ORCID http://orcid.org/0000-0003-2877-6647
Masako MatsumotoDepartment of Internal Medicine, Ito Hospital, Tokyo 150-8308, Japan.
Miho FukushitaDepartment of Internal Medicine, Ito Hospital, Tokyo 150-8308, Japan.ORCID http://orcid.org/0000-0001-6815-5891
Natsuko WatanabeDepartment of Internal Medicine, Ito Hospital, Tokyo 150-8308, Japan.ORCID http://orcid.org/0000-0003-2297-5004
Kiminori SuginoDepartment of Surgery, Ito Hospital, Tokyo 150-8308, Japan.ORCID http://orcid.org/0000-0002-9692-9871
Koichi ItoDepartment of Surgery, Ito Hospital, Tokyo 150-8308, Japan.ORCID http://orcid.org/0000-0002-2341-3620

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the association between a 500 MBq dose of radioactive iodine treatment (RAIT) and both thyroid nodule volume and thyroid function in patients with a single autonomous functioning thyroid nodule (AFTN). We retrospectively studied 201 patients with an AFTN who received RAIT at a dose of 500 MBq and were followed up for more than 2 years. Thyroid function at diagnosis, thyroid antibody positivity, treatment with antithyroid drugs before RAIT, cystic components of the nodule, and

Indexed as

Iodine RadioisotopesThyroid NoduleAdultAgedFemaleFollow-Up StudiesHumansHyperthyroidismHypothyroidismJapanMaleMiddle AgedRetrospective StudiesRisk FactorsThyroid GlandTreatment OutcomeIodine RadioisotopesAutonomous functioning thyroid noduleHyperthyroidismRadioactive iodineVolume reduction

Identifiers

PMID39842794
PMCPMC12086274

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.