Evidence map›Paper›PMID 39841746›Full record

ArticleRevista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo2025

Neonatal mortality of live births with congenital diaphragmatic hernia in São Paulo State, Brazil: Failure of care?

Ana Sílvia Scavacini Marinonio, Milton Harumi Miyoshi, Daniela Testoni Costa Nobre, Adriana Sanudo, Kelsy Catherina Nema Areco, Mandira Daripa Kawakami, Rita de Cássia Xavier Balda, Tulio Konstantyner, Carina Nunes Vieira E Oliveira, Paulo Bandiera-Paiva and 6 more

Abstract read
In one paragraph

Article in Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ana Sílvia Scavacini MarinonioUniversidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-9845-6097
Milton Harumi MiyoshiUniversidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-4935-6505
Daniela Testoni Costa NobreUniversidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-7629-4904
Adriana SanudoUniversidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-1187-0143
Kelsy Catherina Nema ArecoUniversidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-7801-757X
Mandira Daripa KawakamiUniversidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-5230-1989
Rita de Cássia Xavier BaldaUniversidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-7553-466X
Tulio KonstantynerUniversidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-7931-9692
Carina Nunes Vieira E OliveiraUniversidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0009-0003-7086-3696
Paulo Bandiera-PaivaUniversidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-9409-3970
Rosa Maria Vieira de FreitasFundação Sistema Estadual de Análise de Dados, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-4266-6110
Monica La Porte TeixeiraFundação Sistema Estadual de Análise de Dados, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-7571-8154
Bernadette Cunha WaldvogelFundação Sistema Estadual de Análise de Dados, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-5267-7361
Carlos Roberto Veiga KifferUniversidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-1122-0693
Maria Fernanda Branco de AlmeidaUniversidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-5864-3808
Ruth GuinsburgUniversidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-1967-9861

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to analyze if the healthcare organization of perinatal care and availability of referral neonatal intensive care units (NICU) impacted congenital diaphragmatic hernia (CDH) neonatal mortality in the period 2004-2020. This study analyzed the spatial distribution of neonatal deaths of live births with CDH in São Paulo State, Brazil, and its association with NICU beds' availability.

methodsPopulation-based study of all live births in São Paulo State from mothers residing in the same State, from 2004 to 2020. CDH definition was based on WHO-ICD-10 codes; CDH-associated neonatal death was defined as death up to 27 days after birth of infants with CDH. The distribution of CDH-associated neonatal mortality (per 10,000 live births) and NICU beds' availability (≥1 or not available) was mapped, and their association was evaluated by the Mann-Whitney test.

resultsAmong 10,246,686 live births, there were 1378 CDH-associated neonatal deaths across 124/645 (19.2%) municipalities of the State. The median CDH-associated neonatal mortality rate in municipalities with NICU beds was 1.22 (95%CI 0.99-1.51), similar to that found in municipalities with no NICU beds (1.40; 95%CI 1.15-1.67; p=0.224).

conclusionsCDH-associated neonatal deaths were spread throughout São Paulo State with no difference in CDH-associated neonatal mortality rates between municipalities with and without NICU beds available. These findings suggest the necessity of implementing regionalization strategies for CDH perinatal care in the State.

Indexed as

Health Services AccessibilityHernias, Diaphragmatic, CongenitalInfant MortalityIntensive Care Units, NeonatalLive BirthPerinatal CareBrazilFemaleHumansInfantInfant, NewbornMale

Identifiers

PMID39841746
PMCPMC11748498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.