Evidence map›Paper›PMID 39841548›Full record

ArticleExperimental physiology2026

Regional changes in cerebral blood flow between the upright and supine posture and over 3 days of bed rest.

Carmen Possnig, Kyohei Marume, Gautam Babu, Sylvan L J E Janssen, Christopher M Hearon, Katrin A Dias, Satyam Sarma, Justin S Lawley, Benjamin D Levine

Abstract read
In one paragraph

Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carmen PossnigDepartment of Sports Science, Performance Physiology & Prevention, University of Innsbruck, Innsbruck, Austria.
Kyohei MarumeDepartment of Sports Science, Performance Physiology & Prevention, University of Innsbruck, Innsbruck, Austria.
Gautam BabuInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Dallas, Dallas, Texas, USA.
Sylvan L J E JanssenUniversity Medical Center, Radboud University, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0003-3950-0523
Christopher M HearonInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Dallas, Dallas, Texas, USA.
Katrin A DiasInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Dallas, Dallas, Texas, USA.
Satyam SarmaInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Dallas, Dallas, Texas, USA.
Justin S LawleyDepartment of Sports Science, Performance Physiology & Prevention, University of Innsbruck, Innsbruck, Austria.
Benjamin D LevineInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Dallas, Dallas, Texas, USA.ORCID https://orcid.org/0000-0001-9064-7251

Funding

National Space Biomedical Research Institute (NSBRI) CA 00005
6 · The paper itself

Abstract

A reduction in cerebral blood flow (CBF) has been observed during spaceflight and bed rest. We aimed to examine the magnitude and regional heterogeneity of the decrease in CBF during bed rest compared to posture changes on Earth. Seventeen participants (age, 29 ± 9 years, 7 females) were studied in the upright and supine posture and over 3 days of bed rest. We assessed blood flow via duplex ultrasonography in the internal carotid (ICA) and vertebral arteries (VA), and via transcranial Doppler of the middle cerebral artery (MCAv). Mean arterial pressure (MAP) and end-tidal CO

Indexed as

Bed RestCerebrovascular CirculationPostureAdultArterial PressureBlood Flow VelocityBlood PressureCarotid Artery, InternalFemaleHumansMaleMiddle Cerebral ArteryRegional Blood FlowStanding PositionSupine PositionUltrasonography, Doppler, Transcranialbed restcerebral blood flowcerebral hypoperfusionmicrogravityposture changesregional heterogeneity

Identifiers

PMID39841548
PMCPMC13394046

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.