Evidence map›Paper›PMID 39841510›Full record

ArticleJMIR research protocols2025

Assessment of Geriatric Problems and Risk Factors for Delirium in Surgical Medicine: Protocol for Multidisciplinary Prospective Clinical Study.

Henriette Louise Möllmann, Eman Alhammadi, Soufian Boulghoudan, Julian Kuhlmann, Anica Mevissen, Philipp Olbrich, Louisa Rahm, Helmut Frohnhofen

Abstract read
In one paragraph

Article in JMIR research protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Henriette Louise MöllmannDepartment of Oral-, Maxillo- and Plastic Facial Surgery, Heinrich-Heine-University Duesseldorf, Düsseldorf, Germany.ORCID 0000-0002-1040-8814
Eman AlhammadiDepartment of Oral-, Maxillo- and Plastic Facial Surgery, Heinrich-Heine-University Duesseldorf, Düsseldorf, Germany.ORCID 0009-0007-5567-4263
Soufian BoulghoudanHeinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, Düsseldorf, Germany.ORCID 0009-0008-9879-9610
Julian KuhlmannHeinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, Düsseldorf, Germany.ORCID 0009-0009-3897-6635
Anica MevissenHeinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, Düsseldorf, Germany.ORCID 0009-0002-1799-8041
Philipp OlbrichHeinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, Düsseldorf, Germany.ORCID 0009-0002-5773-0269
Louisa RahmHeinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, Düsseldorf, Germany.ORCID 0009-0000-7672-2622
Helmut FrohnhofenOrthopedics and Trauma Surgery, University Hospital Düsseldorf, Düsseldorf, Germany.ORCID 0000-0002-6989-4044

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn aging population in combination with more gentle and less stressful surgical procedures leads to an increased number of operations on older patients. This collectively raises novel challenges due to higher age heavily impacting treatment. A major problem, emerging in up to 50% of cases, is perioperative delirium. It is thus vital to understand whether and which existing geriatric assessments are capable of reliably identifying risk factors, how high the incidence of delirium is, and whether the resulting management of these risk factors might lead to a reduced incidence of delirium.

objectiveThis study aimed to determine the frequency and severity of geriatric medical problems in elective patients of the Clinics of Oral and Maxillofacial Surgery, Vascular Surgery, and Orthopedics, General Surgery, and Trauma Surgery, revealing associations with the incidence of perioperative delirium regarding potential risk factors, and recording the long-term effects of geriatric problems and any perioperative delirium that might have developed later the patient's life.

methodsWe performed both pre- and postoperative assessments in patients of 4 different surgical departments who are older than 70 years. Patient-validated screening instruments will be used to identify risk factors. A geriatric assessment with the content of basal and instrumental activities of daily living (basal activities of daily living [Katz index], instrumental activities of daily living [Lawton and Brody score], cognition [6-item screener and clock drawing test], mobility [de Morton Mobility Index and Sit-to-Stand test], sleep [Pittsburgh Sleep Quality Index and Insomnia Severity Index/STOP-BANG], drug therapy [polypharmacy and quality of medication, Fit For The Aged classification, and anticholinergic burden score], and pain assessment and delirium risk (Delirium Risk Assessment Tool) will be performed. Any medical problems detected will be treated according to current standards, and no intervention is planned as part of the study. In addition, a telephone follow-up will be performed 3, 6, and 12 months after discharge.

resultsRecruitment started in August 2022, with 421 patients already recruited at the time of submission. Initial analyses of the data are to be published at the end of 2024 or the beginning of 2025.

conclusionsIn the current study, we investigate whether the risk factors addressed in the assessment are associated with an increase in the delirium rate. The aim is then to reduce this comprehensive assessment to the central aspects to be able to conduct targeted and efficient risk screening.

trial registrationGerman Clinical Trials Registry DRKS00028614; https://www.drks.de/search/de/trial/DRKS00028614. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/59203.

Indexed as

DeliriumGeriatric AssessmentPostoperative ComplicationsActivities of Daily LivingAgedAged, 80 and overFemaleHumansMaleProspective StudiesRisk Factorsage-related surgical risk factorsagingdeliriumgeriatric assessmentgerontologyhealth informaticsmultidisciplinaryolder patientspalliative careperioperativeperioperative assessmentprospective studyscreeningsurgerysurgical caresurgical medicine

Identifiers

PMID39841510
PMCPMC11799817

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.