Evidence map›Paper›PMID 39841393›Full record

ReviewJournal of fluorescence2025

A Review of Nanomaterials and Microwave Synthesized Metal Oxides Nanoparticles in Schistosomiasis Diagnosis.

Ebenezer Olanrewaju Aluko, Abolanle Saheed Adekunle, John Adekunle Oyekunle, Oluwatobi Samuel Oluwafemi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of fluorescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ebenezer Olanrewaju AlukoDepartment of Chemistry, Faculty of Science, Obafemi Awolowo University, Ile-Ife, Nigeria. ebenezeraluko5@gmail.com.
Abolanle Saheed AdekunleDepartment of Chemistry, Faculty of Science, Obafemi Awolowo University, Ile-Ife, Nigeria. sadekpreto@gmail.com.
John Adekunle OyekunleDepartment of Chemistry, Faculty of Science, Obafemi Awolowo University, Ile-Ife, Nigeria.
Oluwatobi Samuel OluwafemiDepartment of Chemical Sciences, University of Johannesburg, Doornfontein, Johannesburg, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Point of Care (POC) diagnosis provides an effective approach for controlling and managing Neglected Tropical Diseases (NTDs). Electrochemical biosensors are well-suited for molecular diagnostics due to their high sensitivity, cost-effectiveness, and ease of integration into POC devices. Schistosomiasis is a prominent NTD highly prevalent in Africa, Asia, and Latin America, with significant socioeconomic implications such as discrimination, reduced work capacity, or mortality, perpetuating the cycle of poverty in affected regions worldwide. This review explores recent advancements in nanoparticle-based electrochemical biosensors for disease diagnosis, specifically focusing on the schistosome parasite. The synthesis processes and advantages of microwave-assisted preparation of metal oxide nanoparticles are highlighted, showcasing improved purity and energy efficiency compared to traditional combustion methods. In detection prototypes, Schistosome Egg Antigen (SEA) derived from Schistosome mansoni eggs obtained from primary and secondary hosts were evaluated using direct Enzyme-Linked Immunosorbent Assay (ELISA) to measure antibody concentrations in the primary and secondary hosts post-injection. Biosensor system was then developed by modifying developed electrodes with Gold Nanopartcicles (AuNP), Aluminium Gallium Nitride/Gallium Nitride (AlGaN/GaN), Mercaptopropyltrimethoxysilane/Gold Nanoparticles (MPTS/AuNPs) or metal oxide nanoparticles in conjugation with schistosome antibodies, registering current response on interactions with SEA, via cyclic voltammetry (CV), differential pulse voltammetry (DPV), Electrochemical Impedance Spectroscopy (EIS), Amperometry (A) and other electrochemical techniques. This review provides a summary of various constructions of electrochemical biosensors for detecting schistosomiasis.

Indexed as

Biosensing TechniquesMetal NanoparticlesMicrowavesNanostructuresOxidesSchistosomiasisAnimalsElectrochemical TechniquesHumansOxidesDiagnosisElectrochemical biosensorMicrowave-assistedNeglected tropical diseasesPoint of careSchistosome egg antigenVoltammetry

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.