Evidence map›Paper›PMID 39841359›Full record

ArticleSpine deformity2025

The association of congenital diaphragmatic hernia with scoliosis.

Michal Koziara, Stuart Irvine, Nicholas Wei, Prasad Karpe, Paul Rushton, David Fender, Bruce Jaffray

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Article in Spine deformity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michal KoziaraGreat North Children's Hospital, Newcastle Upon Tyne, UK. m.koziara@nhs.net.ORCID http://orcid.org/0009-0003-8922-7630
Stuart IrvineJames Cook University Hospital Foundation Trust, Middlesbrough, UK.
Nicholas WeiJames Cook University Hospital Foundation Trust, Middlesbrough, UK.
Prasad KarpeJames Cook University Hospital Foundation Trust, Middlesbrough, UK.
Paul RushtonGreat North Children's Hospital, Newcastle Upon Tyne, UK.
David FenderGreat North Children's Hospital, Newcastle Upon Tyne, UK.
Bruce JaffrayGreat North Children's Hospital, Newcastle Upon Tyne, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the prevalence of scoliosis in patients who have undergone surgical repair of CDH and attempt to assess the aetiology of scoliosis in affected cases.

methodsA prospectively collected database of patients with CDH treated in a single centre between 1997 and 2023 was reviewed. Cases with adequate records who continued to reside locally having survived beyond age 2 and > 2 years following CDH repair were included. Congenital spinal abnormalities and scoliosis were diagnosed from imaging studies. In those who developed scoliosis, medical notes were reviewed to assess the aetiology of scoliosis and its treatment.

results145 patients (92 male) who had undergone CDH repair were included. The median age at CDH repair was at 4 days. The mean time from CDH repair to this study was 14.1 years (2.0-26.2). 15 developed scoliosis (10.3%). In 8 cases, the scoliosis was considered a reflection of multisystem abnormalities including congenital vertebral anomalies in 3 cases (2%). In the 7 remaining cases the scoliosis had no obvious cause. Of those with scoliosis, to date, 3 have had surgical treatment with 1 awaiting surgery, 7 have not required scoliosis treatment and 4 have died.

conclusionsScoliosis is relatively common in those who have undergone CDH repair, typically presenting before age 10 years. Scoliosis when present was commonly part of a multisystem issue, with congenital vertebral anomalies rare. There appears no strong association between use of synthetic patch and scoliosis. Few children undergoing CDH repair will require treatment of a scoliosis.

Indexed as

Hernia, DiaphragmaticHernias, Diaphragmatic, CongenitalScoliosisAdolescentAdultChildChild, PreschoolFemaleHumansInfantInfant, NewbornMalePrevalenceProspective StudiesYoung AdultCDHCongenitalRepairScoliosisSyndromicThoracogenic

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.