Evidence map›Paper›PMID 39841282›Full record

ArticleLasers in medical science2025

An innovative microwave technology for the treatment of submental skin laxity.

Elena Zappia, Paolo Bonan, Federica Coli, Chiara Del Re, Fortunato Cassalia, Martina Tolone, Luigi Bennardo, Steven Paul Nisticò, Giovanni Cannarozzo

Abstract read
In one paragraph

Article in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elena ZappiaDepartment of Health Sciences, Magna Graecia University, Catanzaro, Italy. elena.zappia@hotmail.it.ORCID http://orcid.org/0009-0005-8167-0325
Paolo BonanLaser Cutaneous Cosmetic & Plastic Surgery Unit, Villa Donatello Clinic, Florence, Italy.
Federica ColiLaser Cutaneous Cosmetic & Plastic Surgery Unit, Villa Donatello Clinic, Florence, Italy.
Chiara Del ReDepartment of Health Sciences, Magna Graecia University, Catanzaro, Italy.
Fortunato CassaliaDepartment of Medicine, University of Padua, Padua, Italy.
Martina ToloneDepartment of Health Sciences, Magna Graecia University, Catanzaro, Italy.
Luigi BennardoDepartment of Health Sciences, Magna Graecia University, Catanzaro, Italy.
Steven Paul NisticòDepartment of Clinical Sciences, Sapienza University of Rome, Rome, Italy.
Giovanni CannarozzoDepartment of Clinical Sciences, Sapienza University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUNDS AND

aimsSubmental skin laxity (SSL), manifesting as sagging skin and double chin, can significantly affect patients' self-perception and social interactions. While surgical treatments exist, non-invasive methods are increasingly sought for their minimal recovery time. This study assesses the safety and effectiveness of a novel microwave-based device for treating SSL, aiming to provide long-term improvements in skin tightness and appearance. MATERIALS AND

methodsTen female patients with moderate to severe SSL underwent two treatments spaced 30 days apart using a 2.45 GHz non-invasive microwave device, with a specific handpiece. Treatment sessions lasted 10 min each, targeting the submental region. The Submental Skin Laxity Grade (SMSLG) was assessed before treatment and 12 weeks after the final session. Safety was monitored, and standardized photographs were taken for clinical evaluation.

resultsAll patients showed a significant reduction in SSL, with SMSLG scores improving from a mean of 3.6 at baseline to 2.3 after 12 weeks. No adverse effects were reported, and patients experienced minimal discomfort during and after the treatment sessions. Photographs revealed visible improvements in skin tone and tightness across all cases.

conclusionsThe microwave-based treatment demonstrated significant efficacy in reducing SSL and improving skin tone with minimal side effects, offering a promising alternative to surgical interventions. This non-invasive approach provides effective outcomes in fewer sessions and may represent a new standard for non-surgical skin tightening in aesthetic dermatology.

Indexed as

Cosmetic TechniquesMicrowavesSkin AgingAdultChinFemaleHumansMiddle AgedFacial agingMicrowaves technologySkin laxitySkin tighteningSubmental fat

Identifiers

PMID39841282
PMCPMC11754354

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.