Evidence map›Paper›PMID 39841169›Full record

ArticleBioconjugate chemistry2025

Effect of Lipidation on the Structure, Oligomerization, and Aggregation of Glucagon-like Peptide 1.

Eva Přáda Brichtová, Irina A Edu, Xinyang Li, Frederik Becher, Ana L Gomes Dos Santos, Sophie E Jackson

Abstract read
In one paragraph

Article in Bioconjugate chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Methyl Proton Spin Relaxation (Analytical chemistry · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eva Přáda BrichtováYusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K.ORCID 0000-0001-9888-6185
Irina A EduYusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K.
Xinyang LiYusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K.
Frederik BecherYusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K.
Ana L Gomes Dos SantosAdvanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Biomedical Campus, Cambridge CB2 0AA, U.K.
Sophie E JacksonYusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K.ORCID 0000-0002-7470-9800

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipidated analogues of glucagon-like peptide 1 (GLP-1) have gained enormous attention as long-acting peptide therapeutics for type 2 diabetes and also antiobesity treatment. Commercially available therapeutic lipidated GLP-1 analogues, semaglutide and liraglutide, have the great advantage of prolonged half-lives

Indexed as

Glucagon-Like Peptide 1LipidsProtein AggregatesHumansProtein MultimerizationSolubilityGlucagon-Like Peptide 1LipidsProtein Aggregates

Identifiers

PMID39841169
PMCPMC11926786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.