Evidence map›Paper›PMID 39840934›Full record

ArticleResuscitation2024

The impact of pediatric post-cardiac arrest care on survival: A multicenter review from the AHA get with the Guidelines®-resuscitation post-cardiac arrest care registry.

Jessica C Fowler, Ryan W Morgan, Amanda O'Halloran, Monique M Gardner, Scott Appel, Heather Wolfe, Martha F Kienzle, Tia T Raymond, Barnaby R Scholefield, Anne-Marie Guerguerian and 6 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Resuscitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jessica C FowlerDepartment of Anesthesiology & Critical Care, Perelman School of Medicine at the University of Pennsylvania, Children's Hospital of Philadelphia 3401 Civic Center Blvd., Philadelphia, PA 19104, USA. Electronic address: fowlerj@chop.edu.
Ryan W MorganDepartment of Anesthesiology & Critical Care, Perelman School of Medicine at the University of Pennsylvania, Children's Hospital of Philadelphia 3401 Civic Center Blvd., Philadelphia, PA 19104, USA.
Amanda O'HalloranDepartment of Anesthesiology & Critical Care, Perelman School of Medicine at the University of Pennsylvania, Children's Hospital of Philadelphia 3401 Civic Center Blvd., Philadelphia, PA 19104, USA.
Monique M GardnerDepartment of Anesthesiology & Critical Care, Perelman School of Medicine at the University of Pennsylvania, Children's Hospital of Philadelphia 3401 Civic Center Blvd., Philadelphia, PA 19104, USA.
Scott AppelCenter for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Blvd. Building 421, Philadelphia, PA 19104, USA.
Heather WolfeDepartment of Anesthesiology & Critical Care, Perelman School of Medicine at the University of Pennsylvania, Children's Hospital of Philadelphia 3401 Civic Center Blvd., Philadelphia, PA 19104, USA.
Martha F KienzleDepartment of Anesthesiology & Critical Care, Perelman School of Medicine at the University of Pennsylvania, Children's Hospital of Philadelphia 3401 Civic Center Blvd., Philadelphia, PA 19104, USA.
Tia T RaymondDepartment of Pediatrics, Pediatric Cardiac Critical Care, Medical City Children's Hospital, 7777 Forest Lane, Dallas, TX 75230, USA.
Barnaby R ScholefieldUniversity of Toronto, The Hospital for Sick Children, 555 University Ave, Toronto, ON MG5 1X8, Canada.
Anne-Marie GuerguerianUniversity of Toronto, The Hospital for Sick Children, 555 University Ave, Toronto, ON MG5 1X8, Canada.
Melania M BembeaJohns Hopkins University School of Medicine, Johns Hopkins Hospital, 1800 Orleans St. Baltimore, MD 21287, USA.
Vinay NadkarniDepartment of Anesthesiology & Critical Care, Perelman School of Medicine at the University of Pennsylvania, Children's Hospital of Philadelphia 3401 Civic Center Blvd., Philadelphia, PA 19104, USA.
Robert A BergDepartment of Anesthesiology & Critical Care, Perelman School of Medicine at the University of Pennsylvania, Children's Hospital of Philadelphia 3401 Civic Center Blvd., Philadelphia, PA 19104, USA.
Robert SuttonDepartment of Anesthesiology & Critical Care, Perelman School of Medicine at the University of Pennsylvania, Children's Hospital of Philadelphia 3401 Civic Center Blvd., Philadelphia, PA 19104, USA.
Alexis A TopjianDepartment of Anesthesiology & Critical Care, Perelman School of Medicine at the University of Pennsylvania, Children's Hospital of Philadelphia 3401 Civic Center Blvd., Philadelphia, PA 19104, USA.
American Heart Association’s Get With The Guidelines®-Resuscitation Investigators

Funding

Pulmonary Hypertension-Associated Pediatric Cardiac ArrestK23HL148541 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI MORGAN, RYAN WILLIAM · 2020 to 2024
$791k
NHLBI NIH HHS K23 HL148541
6 · The paper itself

Abstract

aimAdherence to post-cardiac arrest care (PCAC) recommendations is associated with improved outcomes for adults. We aimed to describe the survival impact of meeting American Heart Association (AHA) PCAC guidelines in children after cardiac arrest.

methodsWe conducted a retrospective study using Get With The Guidelines® Resuscitation's (GWTG®-R) registry to describe the PCAC of patients ≤ 18 years old who suffered an in-hospital or out-of-hospital cardiac arrest (IHCA or OHCA). We evaluated the association between the absence of hypotension and fever in the initial 24 h following return of circulation (ROC) with survival to hospital discharge. We reviewed the utilization of monitoring/evaluation tools recommended in pediatric PCAC guidelines: electrocardiogram (ECG), electroencephalogram (EEG), and neuro-imaging.

resultsWe found 385 pediatric patients who suffered an IHCA or OHCA from 2015 through 2019 and survived at least 6 h post-ROC. Sixty-six percent of patients survived to hospital discharge. Following ROC, 56% of patients had EEG monitoring, 80% had an ECG performed, 47% had a head CT, and 26% had a cerebral MRI. In the initial 24 h post-ROC, 92% of patients did not have hypotension and 79% were afebrile. Patients without hypotension in the initial 24 h post-ROC had higher odds of survival to hospital discharge than those with hypotension (aOR 4.96; 95% CI 2.07, 11.90; p = 0.0003), adjusting for age and cardiac arrest location. Patients without hypotension and without fever in the initial 24 h post-ROC had higher odds of survival to hospital discharge compared to patients who had either hypotension or fever or both (aOR 1.98; 95% CI 1.06,3.71; p = 0.034).

conclusionIn this retrospective multicenter registry study, absence of both post-cardiac arrest hypotension and fever were associated with increased odds of survival to hospital discharge. Further research is needed to understand the full impact of PCAC recommendation compliance on survival outcomes.

Indexed as

Cardiopulmonary ResuscitationGuideline AdherenceOut-of-Hospital Cardiac ArrestAdolescentAmerican Heart AssociationChildChild, PreschoolElectrocardiographyElectroencephalographyFemaleHeart ArrestHumansHypotensionInfantMalePractice Guidelines as TopicCardiac arrestPediatricPost-cardiac arrest careResuscitationSurvival to hospital discharge

Identifiers

PMID39840934
PMCPMC12286579

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.