Observational studyAntimicrobial agents and chemotherapy2025
Prevalence and mortality associated with multidrug-resistant infections in adult intensive care units in Argentina (PREV-AR).
Observational study in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Risk Prediction of Multidrug-Resistant Infections in Pediatric Burn Patients with Hospital-Acquired Infections: A Retrospective Cohort Study.Plastic and reconstructive surgery · 2026Article
- Practice model of unit-based clinical pharmacists' individualized daily antimicrobial use density monitoring report on antimicrobial stewardship in intensive care unit of a tertiary hospital in Guangxi, China: an interrupted time series analysis.Antimicrobial resistance and infection control · 2026Article
- Strategies to prevent cross-transmission of multidrug-resistant microorganisms in intensive care units: A narrative review.Journal of intensive medicine · 2026Review
- Prevalence of Carbapenem-Resistant Gram-Negative Bacilli from Intensive Care Units from Latin America and the Caribbean: A Systematic Review and Meta-Analysis.Antibiotics (Basel, Switzerland) · 2026Review
- Carbapenem-resistantFrontiers in medicine · 2026Article
- Access to Reserve Antibiotics in Latin America and the Caribbean: Situation, Challenges, and Future Directions.Infection and drug resistance · 2026Review
- Development and validation of an interpretable machine learning model for predicting multidrug-resistant infections in ICU patients.Frontiers in cellular and infection microbiology · 2026Article
- Risk Factors and Medical Burden of Multidrug-Resistant Organism Infection in Hospitalized Patients with Pneumonia.Infection and drug resistance · 2026Article
- Impact of Antimicrobial-Resistant Bacterial Pneumonia on In-Hospital Mortality and Length of Hospital Stay: A Retrospective Cohort Study in Spain.Antibiotics (Basel, Switzerland) · 2025Article
- Antibiotic therapy for severe bacterial infections.Intensive care medicine · 2025Review
- Antimicrobial Resistance - The 'Real' Pandemic We Are Unaware Of, Yet Nearby.Journal of Korean medical science · 2025Review
- Prevalence and Associated Mortality of Infections by Multidrug-Resistant Organisms in Pediatric Intensive Care Units in Argentina (PREV-AR-P).Antibiotics (Basel, Switzerland) · 2025Article
- Prevalence of Multidrug-Resistant Organisms During Hospitalization and Its Association with Patient's Functional Status at Discharge: A Retrospective Cohort Study.Inquiry : a journal of medical care organization, provision and financingArticle
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Data from low and middle-income countries (LMICs) on multidrug-resistant microorganisms (MDROs) in intensive care units (ICUs) are scarce. Working in several ICUs in Argentina, we sought to estimate the prevalence and characteristics of MDRO infections and carbapenemase-producing Enterobacterales (CPE) colonization. Mortality associated with MDRO infection was also evaluated. The study was a 24-hour point prevalence study conducted in 164 adult ICUs in Argentina between 24 November and 28 November 2023. The main study outcome was in-ICU mortality and secondary outcomes included the prevalence of MDRO infections, the prevalence of CPE colonization (defined as CPE recovered from a rectal swab), and ICU length of stay (LoS). Mixed effects modeling was used to identify risk factors for in-ICU mortality. Among 1,799 patients, 933 (51.9%) had a reported infection; 599 infections (64.2%) were classified as definite (i.e., with positive cultures) and 334 (35.8%) as probable infection (i.e., negative cultures but signs of infection). Of the 933 patients with infection, 273 (29.2%) had an MDRO recovered with 344 total MDRO cultures recovered. Non-MDRO was recovered from 326 (34.9%) of the 933 patients. Among definite infections, 45.5% (273/599) were due to MDRO with an overall prevalence of MDRO of 15.1% (273 patients with MDRO infections/1,799 patients). CPE colonization, defined as a positive rectal swab taken during the incident hospitalization, occurred in 420/1,696 (24.7%) patients. The most frequent MDRO infection was ventilator-associated pneumonia (100/344; 29.1%). The most common MDRO recovered were carbapenem-resistant
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