Evidence map›Paper›PMID 39840826›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2025

Indirubin-3'-oxime as a dual-action agent: mitigating heat-induced male infertility in

Nguyen Viet Phong, Hyo-Sung Kim, Yan Zhao, Eunbyul Yeom, Seo Young Yang

Abstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nguyen Viet PhongDepartment of Biology Education, Teachers College and Institute for Phylogenomics and Evolution, Kyungpook National University, Daegu, Republic of Korea.ORCID 0000-0003-1715-4455
Hyo-Sung KimSchool of Life Science and Biotechnology, College of Natural Sciences, Kyungpook National University, Daegu, Republic of Korea.
Yan ZhaoSchool of Pharmacy, Yantai University, Yantai, PR China.
Eunbyul YeomSchool of Life Science and Biotechnology, College of Natural Sciences, Kyungpook National University, Daegu, Republic of Korea.
Seo Young YangDepartment of Biology Education, Teachers College and Institute for Phylogenomics and Evolution, Kyungpook National University, Daegu, Republic of Korea.ORCID 0000-0002-5248-1374

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the potential of the indirubin-3'-oxime (I3O) compound to mitigate temperature-induced male infertility in

Indexed as

Enzyme InhibitorsEpoxide HydrolasesIndolesInfertility, MaleOximesAnimalsDose-Response Relationship, DrugDrosophila melanogasterHot TemperatureMaleMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipEnzyme InhibitorsEpoxide Hydrolasesindirubin-3'-monoximeIndolesOximesDrosophila melanogasterIndirubin-3′-oximemale infertilitymolecular dynamicssoluble epoxide hydrolase

Identifiers

PMID39840826
PMCPMC11755746

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.