Evidence map›Paper›PMID 39840651›Full record

ReviewComprehensive reviews in food science and food safety2025

Advances in understanding dietary fiber: Classification, structural characterization, modification, and gut microbiome interactions.

Yiming Feng, Qing Jin, Xuanbo Liu, Tiantian Lin, Andrea Johnson, Haibo Huang

Abstract readReview
In one paragraph

Review in Comprehensive reviews in food science and food safety, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Extrusion-modifiedFood chemistry: X · 2026
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Restoring low-fiber diets-inducedCurrent research in food science · 2026
    Article
  15. Review
  16. Article
  17. Niche partitioning by resource size in the gut microbiome.bioRxiv : the preprint server for biology · 2025
    Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yiming FengDepartment of Food Science and Technology, Virginia Tech, Blacksburg, Virginia, USA.ORCID 0000-0002-9693-3686
Qing JinDepartment of Food Science and Technology, Virginia Tech, Blacksburg, Virginia, USA.
Xuanbo LiuDepartment of Food Science and Technology, Virginia Tech, Blacksburg, Virginia, USA.
Tiantian LinDepartment of Food Science and Technology, Virginia Tech, Blacksburg, Virginia, USA.ORCID 0000-0002-1816-3380
Andrea JohnsonDepartment of Food Science and Technology, Virginia Tech, Blacksburg, Virginia, USA.
Haibo HuangDepartment of Food Science and Technology, Virginia Tech, Blacksburg, Virginia, USA.ORCID 0000-0002-2106-4105

Funding

Foundational and Applied Science Program 2023-67017-39866Institute for Critical Technologies and Applied Science, Virginia TechNational Institute of Food and AgricultureU.S. Department of Agriculture VA-160079Virginia Agricultural Experiment Station, Virginia Polytechnic Institute and State University
6 · The paper itself

Abstract

Gut microbiota and their metabolites profoundly impact host physiology. Targeted modulation of gut microbiota has been a long-term interest in the scientific community. Numerous studies have investigated the feasibility of utilizing dietary fibers (DFs) to modulate gut microbiota and promote the production of health-beneficial bacterial metabolites. However, the complexity of fiber structures, microbiota composition, and their dynamic interactions have hindered the precise prediction of the impact of DF on the gut microbiome. We address this issue with a new perspective, focusing on the inherent chemical and structural complexity of DFs and their interaction with gut microbiota. The chemical and structural complexity of fibers was thoroughly elaborated, encompassing the fibers' molecular composition, polymorphism, mesoscopic structures, porosity, and particle size. Advanced characterization techniques to investigate fiber structural properties were discussed. Additionally, we examined the interactions between DFs and gut microbiota. Finally, we summarized processing techniques to modify fiber structures for improving the fermentability of DF by gut microbiota. The structure of fibers, such as their crystallinity, porosity, degree of branching, and pore wettability, significantly impacts their interactions with gut microbiota. These structural differences also substantially affect fiber's fermentability and capability to modulate the composition of gut microbiota. Conventional approaches are not capable of investigating complex fiber properties and their influences on the gut microbiome; therefore, it is of the essence to involve advanced material characterization techniques and artificial intelligence to unveil more comprehensive information on this topic.

Indexed as

Dietary FiberGastrointestinal MicrobiomeBacteriaFermentationHumansDietary Fibercharacterizationdietary fibersgut microbiomeprocessingstructure

Identifiers

PMID39840651
PMCPMC11752078

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.