Evidence map›Paper›PMID 39840621›Full record

ArticleHua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology2025

Expert consensus on classification and diagnosis of congenital orofacial cleft.

Chenghao Li, Yang An, Xiaohong Duan, Yingkun Guo, Shanling Liu, Hong Luo, Duan Ma, Yunyun Ren, Xudong Wang, Xiaoshan Wu and 4 more

Abstract readConsensus Statement
In one paragraph

Article in Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Chenghao LiState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Dept. of Cleft Lip and Palate Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Yang AnDept. of Plastic Surgery, Peking University Third Hospital, Beijing 100191, China.
Xiaohong DuanClinic of Oral Rare Diseases and Genetic Diseases, School of Stomatology, Air Force Medical University, Xi'an 710032, China.
Yingkun GuoDept. of Radiology, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Shanling LiuDept. of Medical Genetics/Dept. of Birth Defects and Related Diseases of Women and Children, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Hong LuoDept. of Ultrasonography/Dept. of Birth Defects and Related Diseases of Women and Children, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Duan MaLab of Birth Defects Research, Fudan University, Shanghai 200438, China.
Yunyun RenDept. of Ultrasonics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200090, China.
Xudong WangDept. of Oral and Craniomaxillofacial Surgery, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200011, China.
Xiaoshan WuDept. of Oral and Maxillofacial Surgery, Xiangya Hospital of Central South University, Changsha 410008, China.
Hongning XieDept. of Medical Ultrasonics, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China.
Hongping ZhuDept. of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China.
Jun ZhuNational Center for Birth Defect Monitoring, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Bing ShiState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Dept. of Cleft Lip and Palate Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital orofacial cleft, the most common birth defect in the maxillofacial region, exhibits a wide range of prognosis depending on the severity of deformity and underlying etiology. Non-syndromic congenital orofacial clefts typically present with milder deformities and more favorable treatment outcomes, whereas syndromic congenital orofacial clefts often manifest with concomitant organ abnormalities, which pose greater challenges for treatment and result in poorer prognosis. This consensus provides an elaborate classification system for varying degrees of orofacial clefts along with corresponding diagnostic and therapeutic guidelines. Results serve as a crucial resource for families to navigate prenatal screening results or make informed decisions regarding treatment options while also contributing significantly to preventing serious birth defects within the development of population.

Indexed as

Cleft LipCleft PalateConsensusFemaleHumansPrenatal Diagnosisclassificationcongenital orofacial cleftdiagnosis and therapy

Identifiers

PMID39840621
PMCPMC11917503

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.