Evidence map›Paper›PMID 39840577›Full record

SynthesisThe International journal of social psychiatry2025

Functioning, disability, and health of individuals with Hikikomori (prolonged social withdrawal) and their families: A systematic review and meta-analysis of case-control studies.

Shunsuke Nonaka, Hiroaki Kubo, Tomoya Takeda, Motohiro Sakai

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The International journal of social psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Association Between Loneliness and Hikikomori Symptoms. A Systematic Review and Meta-Analysis.International journal of methods in psychiatric research · 2026
    Pooled it
  2. Pooled it
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  10. Hikikomori Risk in the UK.The International journal of social psychiatry · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shunsuke NonakaSchool of Child Psychology, Tokyo Future University, Tokyo, Japan.ORCID 0000-0001-9040-4436
Hiroaki KuboFaculty of Medicine, University of Miyazaki, Miyazaki, Japan.ORCID 0000-0001-7725-527X
Tomoya TakedaDepartment of Psychological Sciences, University of Human Environments, Ehime, Japan.
Motohiro SakaiFaculty of Education, University of Miyazaki, Miyazaki, Japan.ORCID 0000-0002-7944-3001

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrently, paradoxical findings exist regarding the level of functioning in individuals with Hikikomori (prolonged social withdrawal).

aimsThis systematic review aimed to clarify the functioning, disability, and health of individuals with Hikikomori and their families in comparison to those without Hikikomori.

methodRelevant studies were searched from April 22 to 25, 2022, using MEDLINE, PsycINFO, Scopus, and two Japanese databases. Functions were categorized into 'body functions"; "structure"; and "activity and participation', which were further classified into subcategories.

resultsOf the 8,181 studies screened, 24 studies with 1,769 individuals with Hikikomori were included. Twelve, three, and four indicators from six studies on depression and anxiety, three on addiction, and two on thought problem symptoms, respectively, were higher in the Hikikomori group than in the comparison group, with at least moderate effect sizes. Three indicators from three studies on interpersonal relationships were worse in the Hikikomori group, with at least moderate effect sizes. The meta-analyses showed that internalizing symptoms, externalizing symptoms, and thought disorders were significantly higher in the Hikikomori group than those in the comparison group with moderate-to-high effect sizes. Contrastingly, communication/interpersonal interactions were significantly lower in the Hikikomori group than those in the comparison group. No significant differences were observed in daily life/social life and the families' communication/interpersonal interactions and relationship.

conclusionsThe study limitations include a high risk of bias and heterogeneity. Overall, individuals with Hikikomori often have impaired mental and interpersonal interaction functions; thus, comorbidities of this condition should be carefully assessed. PROSPERO: CRD42022320592.

Indexed as

FamilyHealth StatusSocial IsolationCase-Control StudiesHumansInterpersonal Relationsand healthCulturedisabilityinternational classification of functioninginterpersonal relationsmental healthsystematic review

Identifiers

PMID39840577
PMCPMC12171063

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.