ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025
CTB6 Confers Cold Tolerance at the Booting Stage by Maintaining Tapetum Development in Rice.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- SDR3.1 negatively regulates seed dormancy in Poaceae crops.The Plant journal : for cell and molecular biology · 2026Article
- Innovations in hybrid rice seed production: Integrating agronomy, mechanization, and biotechnology.Plant communications · 2026Review
- Loss of the plastidial hexokinase CsHXK3 triggers metabolic starvation and ROS imbalance leading to pollen abortion in cucumber.The Plant journal : for cell and molecular biology · 2026Article
- The Rice Cis-Natural Antisense Transcript NAT1850 of Pri-miR1850 Negatively Regulates Cold Tolerance by Repressing NPR3.Plant biotechnology journal · 2026Article
- The Pentatricopeptide Repeat Protein OsPPR7 Confers Cold Tolerance at the Booting Stage in Rice by Regulating ABA and ROS Homeostasis.Rice (New York, N.Y.) · 2026Article
- Research progress on cold tolerance key genes and mechanisms in four major northern China crops.Frontiers in plant science · 2026Review
- Combining QTL mapping and transcriptomics to identify candidate genes for cold tolerance during the budding and seedling stages in rice.BMC genomics · 2025Article
- Rice-specific miR1850.1 targets NPR3 to regulate cold stress response.Plant communications · 2025Article
- Suppressing an auxin efflux transporter enhances rice adaptation to temperate habitats.Nature communications · 2025Article
- CTB6 Confers Cold Tolerance at the Booting Stage by Maintaining Tapetum Development in Rice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Integrating RNA-Seq and linkage mapping to identify and characterizeFrontiers in plant science · 2025Article
- Cold stress in rice (Frontiers in plant science · 2025Review
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Authors and funding
19 authors.
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Abstract
Rice is highly sensitive to cold stress, particularly at the booting stage, which significantly threatens rice production. In this study, we cloned a gene, CTB6, encoding a lipid transfer protein involved in cold tolerance at the booting stage in rice, based on our previous fine-mapped quantitative trait locus (QTL) qCTB10-2. CTB6 is mainly expressed in the tapetum and young microspores of the anther. CTB6 interacts with catalases (CATs) to maintain their stability, thereby scavenging reactive oxygen species (ROS) accumulation in anthers and facilitating tapetum development under cold stress conditions. Additionally, CTB6 has lipid-binding ability and affects the lipid content in anthers to regulate cold tolerance at the booting stage. Haplotype analysis and promoter activity assay revealed a specific single nucleotide polymorphism (SNP)-489 variation in the promoter of CTB6, which enhances its expression and results in improved cold tolerance in Hap1-K varieties. The CTB6 near-isogenic line (NIL) exhibited enhanced cold tolerance at the booting stage, with no significant effects on other agronomic traits. Our findings uncover a natural variation of CTB6 for cold tolerance at the booting stage and provide new genetic resources for cold tolerance breeding in rice.
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