Evidence map›Paper›PMID 39840485›Full record

SynthesisScience progress

Ahmed glaucoma valve implant for refractory glaucoma in children: A systematic review and meta-analysis.

Xiangjun Fu, Juan He, Guoliang Li, Hongyi Luo, Ruijue Peng, Yilian Cheng, Jie Peng, Shiyan Chen, Chao Qu

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiangjun FuSchool of Medicine, University of Electronic Science and Technology of China, Chengdu, China.ORCID 0000-0002-4111-5838
Juan HeSchool of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Guoliang LiChengdu University of Traditional Chinese Medicine, Chengdu, China.
Hongyi LuoChengdu University of Traditional Chinese Medicine, Chengdu, China.
Ruijue PengSchool of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Yilian ChengDepartment of Ophthalmology, Sichuan Provincial People's Hospital,Chengdu, China.
Jie PengDepartment of Ophthalmology, Sichuan Provincial People's Hospital,Chengdu, China.
Shiyan ChenDepartment of Ophthalmology, Sichuan Provincial People's Hospital,Chengdu, China.
Chao QuSchool of Medicine, University of Electronic Science and Technology of China, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate the efficacy and safety of the Ahmed glaucoma valve in pediatric patients with refractory glaucoma.

methodsA comprehensive literature search was conducted across multiple major databases, including PubMed, Embase, the Cochrane Library of Systematic Reviews, Science Direct, China's National Knowledge Infrastructure, and the Wanfang database. We retrieved studies published before December 2022 that met the inclusion criteria, including clinical controlled trials (randomized controlled trials) and clinical noncontrolled trials (non-randomized controlled trials) on the use of Ahmed glaucoma valve in pediatric patients with refractory glaucoma. We performed a meta-analysis and systematic review. The efficacy measures included intraocular pressure, number of anti-glaucoma medications, visual acuity, and success rate. The safety measures were complications. Statistical analysis was performed using RevMan 5.0 software.

resultsWe identified 46 eligible studies: Compared with geographic location and study type, the Ahmed glaucoma valve showed a decrease in postoperative intraocular pressure and number of anti-glaucoma medications compared to preoperative levels in children with refractory glaucoma (

conclusionsThe Ahmed glaucoma valve implantation has some effectiveness in reducing intraocular pressure in children with refractory glaucoma, but there are still many complications. Valve model may not be the key factor affecting the postoperative effectiveness and adverse reactions of refractory glaucoma in children.

Indexed as

GlaucomaGlaucoma Drainage ImplantsChildHumansIntraocular PressureTreatment OutcomeVisual AcuityAhmed glaucoma valve implantationchildhoodmeta-analysisRefractory glaucomasystematic review

Identifiers

PMID39840485
PMCPMC11752183

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.