Evidence map›Paper›PMID 39840431›Full record

ArticleCirculation research2025

TRIPLE Score: GPVI and CD36 Expression Predict a Prothrombotic Platelet Function Phenotype.

Alexander P Bye, Neline Kriek, Carly Kempster, Joanne L Dunster, Joanne L Mitchell, Tanya Sage, Suzannah Rawlings, Maria V Diaz Alonso, Valentina Shpakova, Abigail Whyte and 12 more

Abstract readLetter
In one paragraph

Article in Circulation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Platelet Membrane Receptors and Signalling Pathways.Handbook of experimental pharmacology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Alexander P ByeSchool of Pharmacy, School of Chemistry Food and Pharmacy (A.P.B.), University of Reading, United Kingdom.ORCID 0000-0002-2061-2253
Neline KriekSchool of Biological Sciences and Institute for Cardiovascular and Metabolic Research, (A.P.B., N.K., C.K., J.L.D., T.S., S.R., M.V.D.A., V.S., N.R., C.I.J., J.M.G.), University of Reading, United Kingdom.ORCID 0000-0002-7324-0799
Carly KempsterSchool of Biological Sciences and Institute for Cardiovascular and Metabolic Research, (A.P.B., N.K., C.K., J.L.D., T.S., S.R., M.V.D.A., V.S., N.R., C.I.J., J.M.G.), University of Reading, United Kingdom.ORCID 0000-0001-5721-1050
Joanne L DunsterSchool of Biological Sciences and Institute for Cardiovascular and Metabolic Research, (A.P.B., N.K., C.K., J.L.D., T.S., S.R., M.V.D.A., V.S., N.R., C.I.J., J.M.G.), University of Reading, United Kingdom.ORCID 0000-0001-8986-4902
Joanne L MitchellInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, United Kingdom (J.L.M.).
Tanya SageSchool of Biological Sciences and Institute for Cardiovascular and Metabolic Research, (A.P.B., N.K., C.K., J.L.D., T.S., S.R., M.V.D.A., V.S., N.R., C.I.J., J.M.G.), University of Reading, United Kingdom.ORCID 0009-0000-9745-273X
Suzannah RawlingsSchool of Biological Sciences and Institute for Cardiovascular and Metabolic Research, (A.P.B., N.K., C.K., J.L.D., T.S., S.R., M.V.D.A., V.S., N.R., C.I.J., J.M.G.), University of Reading, United Kingdom.
Maria V Diaz AlonsoSchool of Biological Sciences and Institute for Cardiovascular and Metabolic Research, (A.P.B., N.K., C.K., J.L.D., T.S., S.R., M.V.D.A., V.S., N.R., C.I.J., J.M.G.), University of Reading, United Kingdom.ORCID 0009-0009-4887-099X
Valentina ShpakovaSchool of Biological Sciences and Institute for Cardiovascular and Metabolic Research, (A.P.B., N.K., C.K., J.L.D., T.S., S.R., M.V.D.A., V.S., N.R., C.I.J., J.M.G.), University of Reading, United Kingdom.ORCID 0000-0002-9304-7099
Abigail WhyteUniversity Department of Cardiology, Royal Berkshire Hospital, Reading, United Kingdom (A.W., L.D., S.M., M.B., N.R., C.M.).
Leanne DymottUniversity Department of Cardiology, Royal Berkshire Hospital, Reading, United Kingdom (A.W., L.D., S.M., M.B., N.R., C.M.).
Sharon MarkUniversity Department of Cardiology, Royal Berkshire Hospital, Reading, United Kingdom (A.W., L.D., S.M., M.B., N.R., C.M.).
Mark BruntonUniversity Department of Cardiology, Royal Berkshire Hospital, Reading, United Kingdom (A.W., L.D., S.M., M.B., N.R., C.M.).
Joana BatistaDepartment of Haematology, University of Cambridge, Cambridge Biomedical Campus, United Kingdom (J.B., H.M.K., P.T., K.D.).ORCID 0000-0001-5406-6353
Harriet McKinneyDepartment of Haematology, University of Cambridge, Cambridge Biomedical Campus, United Kingdom (J.B., H.M.K., P.T., K.D.).
Patrick ThomasDepartment of Haematology, University of Cambridge, Cambridge Biomedical Campus, United Kingdom (J.B., H.M.K., P.T., K.D.).
Kate DownesDepartment of Haematology, University of Cambridge, Cambridge Biomedical Campus, United Kingdom (J.B., H.M.K., P.T., K.D.).
Amanda J UnsworthDiscovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (A.J.U.).ORCID 0000-0003-3809-5984
Neil RupareliaSchool of Biological Sciences and Institute for Cardiovascular and Metabolic Research, (A.P.B., N.K., C.K., J.L.D., T.S., S.R., M.V.D.A., V.S., N.R., C.I.J., J.M.G.), University of Reading, United Kingdom.ORCID 0000-0003-3968-2750
Charlie McKennaUniversity Department of Cardiology, Royal Berkshire Hospital, Reading, United Kingdom (A.W., L.D., S.M., M.B., N.R., C.M.).ORCID 0000-0001-7367-8937
Chris I JonesSchool of Biological Sciences and Institute for Cardiovascular and Metabolic Research, (A.P.B., N.K., C.K., J.L.D., T.S., S.R., M.V.D.A., V.S., N.R., C.I.J., J.M.G.), University of Reading, United Kingdom.
Jonathan M GibbinsSchool of Biological Sciences and Institute for Cardiovascular and Metabolic Research, (A.P.B., N.K., C.K., J.L.D., T.S., S.R., M.V.D.A., V.S., N.R., C.I.J., J.M.G.), University of Reading, United Kingdom.ORCID 0000-0002-0372-5352

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

blood plateletscollagenphenotypeplatelet activationplatelet function testsriskthrombosis

Identifiers

PMID39840431
PMCPMC11825475

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.