ArticleHemaSphere2025
Detection of clinically relevant variants in the
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Article in HemaSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- ComplexInternational journal of molecular sciences · 2026Review
- Human adipose-derived mesenchymal stromal cells in vitro expansion for regenerative applications: tracking small genetic variants reveals dynamic changes within a genetically stable framework.Stem cell research & therapy · 2026Article
- Review
- Nodal Marginal Zone Lymphoma with Prominent Expansion of PD-1+ T-Follicular Helper Cells: A Persistent Diagnostic Challenge with a Heterogeneous Mutational Architecture.International journal of molecular sciences · 2025Article
- Methodological Assessment of High-Throughput Sequencing Platforms: Illumina vs. MGI in Clinical-GradeInternational journal of molecular sciences · 2025Article
- ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-2024 update.Leukemia · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
99 authors.
Sarka PavlovaDepartment of Internal Medicine, Hematology and Oncology, and Institute of Medical Genetics and Genomics, University Hospital Brno and Medical Faculty Masaryk University Brno Czech Republic.ORCID https://orcid.org/0000-0003-1528-9743
Jitka MalcikovaDepartment of Internal Medicine, Hematology and Oncology, and Institute of Medical Genetics and Genomics, University Hospital Brno and Medical Faculty Masaryk University Brno Czech Republic.ORCID https://orcid.org/0000-0003-3650-6698
Lenka RadovaCentre for Molecular Medicine, Central European Institute of Technology (CEITEC) Masaryk University Brno Czech Republic.ORCID https://orcid.org/0000-0001-8103-148X
Silvia BonfiglioB-Cell Neoplasia Unit and Strategic Research Program on CLL IRCCS Ospedale San Raffaele Milan Italy.
Jack B CowlandDepartment of Clinical Genetics, Centre of Diagnostic Investigations Copenhagen University Hospital - Rigshospitalet Copenhagen Denmark.
Christian BrieghelDepartment of Hematology Copenhagen University Hospital - Rigshospitalet Copenhagen Denmark.
Mette K AndersenDepartment of Clinical Genetics, Centre of Diagnostic Investigations Copenhagen University Hospital - Rigshospitalet Copenhagen Denmark.
Maria KarypidouInstitute of Applied Biosciences Centre for Research and Technology Hellas Thessaloniki Greece.
Bella BidermanNational Medical Research Center for Hematology Moscow Russia.ORCID https://orcid.org/0000-0002-6253-3334
Michael DoubekDepartment of Internal Medicine, Hematology and Oncology, and Institute of Medical Genetics and Genomics, University Hospital Brno and Medical Faculty Masaryk University Brno Czech Republic.ORCID https://orcid.org/0000-0002-1269-6282
Gregory LazarianHematology laboratory HUPSSD, Hôpital Avicenne, APHP Bobigny France.ORCID https://orcid.org/0000-0002-4315-3440
Inmaculada RapadoDepartment of Hematology Hospital Universitario 12 de Octubre, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Complutense University, CNIO, CIBERONC Madrid Spain.
Matthijs VynckDepartment of Laboratory Medicine AZ Sint-Jan Hospital Bruges Belgium.ORCID https://orcid.org/0000-0001-9875-385X
Naomi A PorretDepartment of Hematology and Central Hematology Laboratory, Inselspital Bern University Hospital, University of Bern Bern Switzerland.ORCID https://orcid.org/0000-0002-2515-1935
Martin AndresDepartment of Hematology and Central Hematology Laboratory, Inselspital Bern University Hospital, University of Bern Bern Switzerland.ORCID https://orcid.org/0000-0001-9891-2988
Dina RosenbergHematology Laboratory Rambam Medical Center Haifa Israel.
Dvora SaharHematology Laboratory Rambam Medical Center Haifa Israel.
Carolina Martínez-LapercheDepartment of Hematology Gregorio Marañón General University Hospital, Gregorio Marañón Health Research Institute (IiSGM) Madrid Spain.
Ismael BuñoDepartment of Hematology Gregorio Marañón General University Hospital, Gregorio Marañón Health Research Institute (IiSGM) Madrid Spain.
Andrew HindleyHaematology Department Belfast City Hospital Belfast UK.
David DonaldsonHaematology Department Belfast City Hospital Belfast UK.
Julio B SánchezMolecular Cytogenetics Unit, Hematology Department Hospital Universitario Puerta de Hierro-Majadahonda Madrid Spain.
José A García-MarcoMolecular Cytogenetics Unit, Hematology Department Hospital Universitario Puerta de Hierro-Majadahonda Madrid Spain.
Alicia Serrano-AlcaláHematology Department Hospital Clínico Universitario-INCLIVA Valencia Spain.ORCID https://orcid.org/0000-0002-3392-4336
Blanca Ferrer-LoresHematology Department Hospital Clínico Universitario-INCLIVA Valencia Spain.
Concepción Fernández-RodriguezPathology Department Hospital del Mar, IMIM (Hospital del Mar Medical Research Institute) Barcelona Spain.ORCID https://orcid.org/0000-0002-5853-0843
Beatriz BellosilloPathology Department Hospital del Mar, IMIM (Hospital del Mar Medical Research Institute) Barcelona Spain.
Stephan StilgenbauerDepartment of Internal Medicine III Ulm University Ulm Germany.
Eugen TauschDepartment of Internal Medicine III Ulm University Ulm Germany.
Hero NikdinDepartment of Molecular Medicine and Surgery Karolinska Institutet Stockholm Sweden.
Fiona QuinnCancer Molecular Diagnostics Department Centre for Laboratory Medicine and Molecular Pathology, St. James Hospital Dublin Ireland.
Emer AtkinsonCancer Molecular Diagnostics Department Centre for Laboratory Medicine and Molecular Pathology, St. James Hospital Dublin Ireland.
Lisette van de CorputCentral Diagnostic Laboratory University Medical Center Utrecht Utrecht The Netherlands.
Cafer YildizCentral Diagnostic Laboratory University Medical Center Utrecht Utrecht The Netherlands.
Cristina Bilbao-SieyroServicio de Hematología Hospital Universitario de Gran Canaria Dr. Negrín, Departamento de Morfología de La Universidad de Las Palmas de Gran Canaria Gran Canaria Spain.
Yanira FloridoServicio de Hematología Hospital Universitario de Gran Canaria Dr. Negrín, Departamento de Morfología de La Universidad de Las Palmas de Gran Canaria Gran Canaria Spain.
Christian ThiedeAgenDix GmbH Dresden Germany.
Caroline SchusterAgenDix GmbH Dresden Germany.
Anastazja StojDepartment of Hematological Diagnostics and Genetics University Hospital in Krakow Krakow Poland.ORCID https://orcid.org/0000-0002-7428-577X
Sylwia CzekalskaDepartment of Hematological Diagnostics and Genetics University Hospital in Krakow Krakow Poland.ORCID https://orcid.org/0009-0007-3736-7577
Anastasia ChatzidimitriouInstitute of Applied Biosciences Centre for Research and Technology Hellas Thessaloniki Greece.
Stamatia LaidouInstitute of Applied Biosciences Centre for Research and Technology Hellas Thessaloniki Greece.ORCID https://orcid.org/0000-0002-4636-1579
Audrey BidetLaboratoire d'Hématologie Biologique CHU Bordeaux Bordeaux France.ORCID https://orcid.org/0000-0003-0992-8377
Charles DussiauLaboratoire d'Hématologie Biologique CHU Bordeaux Bordeaux France.
Friedel NolletDepartment of Laboratory Medicine AZ Sint-Jan Hospital Bruges Belgium.
Giovanna PirasLaboratorio specialistico UOC ematologia Ospedale San Francesco ASL Nuoro Italy.
Maria MonneLaboratorio specialistico UOC ematologia Ospedale San Francesco ASL Nuoro Italy.
Svetlana SmirnovaNational Medical Research Center for Hematology Moscow Russia.ORCID https://orcid.org/0000-0001-6220-8868
Eugene NikitinOutpatient department of Hematology, Oncology and Chemotherapy, Botkin Hospital, and Department of Hematology and Transfusiology Russian Medical Academy of Continuous Professional Education Moscow Russia.ORCID https://orcid.org/0000-0002-2490-1263
Ivan SlomaUniv Paris Est Creteil, INSERM, IMRB Creteil France.
Alexis ClaudelUniv Paris Est Creteil, INSERM, IMRB Creteil France.
Laetitia LargeaudInstitut Universitaire de Cancérologie de Toulouse Toulouse France.ORCID https://orcid.org/0000-0001-5341-5427
Loïc YsebaertInstitut Universitaire de Cancérologie de Toulouse Toulouse France.ORCID 0000-0003-4102-7261
Peter J M ValkDepartment of Hematology, Erasmus MC Cancer Institute University Medical Center Rotterdam Rotterdam The Netherlands.ORCID https://orcid.org/0000-0002-8857-9461
Amy ChristianMolecular Pathology University Hospitals Dorset Bournemouth UK.
Renata WalewskaMolecular Pathology University Hospitals Dorset Bournemouth UK.
David OscierMolecular Pathology University Hospitals Dorset Bournemouth UK.
Marta SebastiãoLaboratório Hemato-Oncologia Instituto Português de Oncologia de Lisboa Lisbon Portugal.ORCID https://orcid.org/0000-0002-5070-1599
Maria Gomes da SilvaServiço de Hematologia Instituto Português de Oncologia de Lisboa Lisbon Portugal.ORCID https://orcid.org/0000-0002-6993-2450
Piero GalieniUOC Hematology Mazzoni Hospital-Ascoli Piceno Ascoli Piceno Italy.
Mario AngeliniUOC Hematology Mazzoni Hospital-Ascoli Piceno Ascoli Piceno Italy.
Davide RossiInstitute of Oncology Research and Oncology Institute of Southern Switzerland Bellinzona Switzerland.
Valeria SpinaLaboratorio di Diagnostica Molecolare, Servizio di Genetica Medica EOLAB Ente Ospedaliero Cantonale Bellinzona Switzerland.
Sónia MatosGenomed-Diagnósticos de Medicina Molecular iMM - Instituto de Medicina Molecular, Faculdade de Medicina Lisboa Portugal.
Vânia MartinsGenomed-Diagnósticos de Medicina Molecular iMM - Instituto de Medicina Molecular, Faculdade de Medicina Lisboa Portugal.
Tomasz StokłosaDepartment of Tumor Biology and Genetics Medical University of Warsaw Warsaw Poland.ORCID https://orcid.org/0000-0001-6918-5056
Monika PepekDepartment of Tumor Biology and Genetics Medical University of Warsaw Warsaw Poland.ORCID https://orcid.org/0000-0003-3506-8040
Panagiotis BaliakasDepartment of Immunology, Genetics and Pathology Uppsala University Uppsala Sweden.
Rafa AndreuHematology Department Hospital Universitari i Politècnic la Fe Valencia Spain.
Irene LunaHematology Department Hospital Universitari i Politècnic la Fe Valencia Spain.
Tiina KahreDepartment of Laboratory Genetics, Genetics and Personalized Clinic Tartu University Hospital Tartu Estonia.ORCID https://orcid.org/0009-0007-4399-354X
Ülle MurumetsDepartment of Laboratory Genetics, Genetics and Personalized Clinic Tartu University Hospital Tartu Estonia.
Tereza PikousovaCentre for Molecular Medicine, Central European Institute of Technology (CEITEC) Masaryk University Brno Czech Republic.
Terezia KurucovaCentre for Molecular Medicine, Central European Institute of Technology (CEITEC) Masaryk University Brno Czech Republic.ORCID https://orcid.org/0009-0008-7110-5543
Sophie LairdWessex Genomics Laboratory Service Salisbury NHS Foundation Trust Salisbury UK.
Daniel WardWessex Genomics Laboratory Service Salisbury NHS Foundation Trust Salisbury UK.
Miguel AlcocebaDepartment of Hematology University Hospital of Salamanca (HUS/IBSAL), CIBERONC and Cancer Research Center of Salamanca-IBMCC (USAL-CSIC) Salamanca Spain.ORCID 0000-0002-3819-4846
Ana BalanzateguiDepartment of Hematology University Hospital of Salamanca (HUS/IBSAL), CIBERONC and Cancer Research Center of Salamanca-IBMCC (USAL-CSIC) Salamanca Spain.ORCID 0000-0003-0660-8183
Lydia ScarfoB-Cell Neoplasia Unit and Strategic Research Program on CLL IRCCS Ospedale San Raffaele Milan Italy.
Francesca GandiniB-Cell Neoplasia Unit and Strategic Research Program on CLL IRCCS Ospedale San Raffaele Milan Italy.
Ettore ZapparoliCenter for Omics Sciences IRCCS Ospedale San Raffaele Milan Italy.ORCID https://orcid.org/0000-0003-4170-7902
Adoración BlancoDepartment of Hematology Hospital Universitari Vall d'Hebron (HUVH) Barcelona Spain.
Pau AbrisquetaDepartment of Hematology Hospital Universitari Vall d'Hebron (HUVH) Barcelona Spain.
Ana E Rodríguez-VicenteOncohematology Research Group, Institute of Biomedical Research of Salamanca (IBSAL) Cancer Research Centre (IBMCC, USAL-CSIC) and University of Salamanca Salamanca Spain.ORCID https://orcid.org/0000-0001-6516-2172
Rocío BenitoOncohematology Research Group, Institute of Biomedical Research of Salamanca (IBSAL) Cancer Research Centre (IBMCC, USAL-CSIC) and University of Salamanca Salamanca Spain.ORCID https://orcid.org/0000-0001-9781-4198
Clotilde BravettiDepartment of Biological Hematology Sorbonne Université, AP-HP, Pitié-Salpêtrière Hospital Paris France.
Frédéric DaviDepartment of Biological Hematology Sorbonne Université, AP-HP, Pitié-Salpêtrière Hospital Paris France.
Paula GameiroLaboratório Hemato-Oncologia Instituto Português de Oncologia de Lisboa Lisbon Portugal.ORCID https://orcid.org/0000-0002-3761-7050
Joaquin Martinez-LopezDepartment of Hematology Hospital Universitario 12 de Octubre, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Complutense University, CNIO, CIBERONC Madrid Spain.
Bárbara Tazón-VegaDepartment of Hematology Hospital Universitari Vall d'Hebron (HUVH) Barcelona Spain.
Fanny Baran-MarszakHematology laboratory HUPSSD, Hôpital Avicenne, APHP Bobigny France.
Zadie DavisMolecular Pathology University Hospitals Dorset Bournemouth UK.
Mark CatherwoodHaematology Department Belfast City Hospital Belfast UK.
Andrey SudarikovNational Medical Research Center for Hematology Moscow Russia.ORCID https://orcid.org/0000-0001-9463-9187
Richard RosenquistDepartment of Molecular Medicine and Surgery Karolinska Institutet Stockholm Sweden.ORCID 0000-0002-0211-8788
Carsten U NiemannDepartment of Hematology Copenhagen University Hospital - Rigshospitalet Copenhagen Denmark.
Kostas StamatopoulosInstitute of Applied Biosciences Centre for Research and Technology Hellas Thessaloniki Greece.
Paolo GhiaB-Cell Neoplasia Unit and Strategic Research Program on CLL IRCCS Ospedale San Raffaele Milan Italy.ORCID 0000-0003-3750-7342
Sarka PospisilovaDepartment of Internal Medicine, Hematology and Oncology, and Institute of Medical Genetics and Genomics, University Hospital Brno and Medical Faculty Masaryk University Brno Czech Republic.ORCID https://orcid.org/0000-0001-7136-2680
Funding
No grant is acknowledged in the PubMed record.
Abstract
In chronic lymphocytic leukemia, the reliability of next-generation sequencing (NGS) to detect
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.