Evidence map›Paper›PMID 39839853›Full record

ArticleFrontiers in neuroinformatics2024

The Multicentre Acute ischemic stroke imaGIng and Clinical data (MAGIC) repository: rationale and blueprint.

Hakim Baazaoui, Stefan T Engelter, Henrik Gensicke, Lukas S Enz, Marios Psychogios, Matthias Mutke, Patrik Michel, Davide Strambo, Alexander Salerno, Henk A Marquering and 16 more

Abstract read
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In one paragraph

Article in Frontiers in neuroinformatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Hakim BaazaouiDepartment of Neurology, University Hospital Zurich, Zurich, Switzerland.
Stefan T EngelterNeurorehabilitation and Neurology, University Department of Geriatric Medicine Felix Platter, University of Basel, Basel, Switzerland.
Henrik GensickeNeurorehabilitation and Neurology, University Department of Geriatric Medicine Felix Platter, University of Basel, Basel, Switzerland.
Lukas S EnzDepartment of Neurology and Stroke Center, University of Basel and University Hospital Basel, Basel, Switzerland.
Marios PsychogiosDepartment of Clinical Research, University of Basel, Basel, Switzerland.
Matthias MutkeDepartment of Clinical Research, University of Basel, Basel, Switzerland.
Patrik MichelStroke Center, Neurology Service, Department of Neurological Sciences, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Davide StramboStroke Center, Neurology Service, Department of Neurological Sciences, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Alexander SalernoStroke Center, Neurology Service, Department of Neurological Sciences, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Henk A MarqueringRadiology and Nuclear Medicine/Biomedical Engineering and Physics, Amsterdam University Medical Centers, Amsterdam, Netherlands.
Paul J NederkoornDepartment of Neurology, Amsterdam University Medical Centers, Amsterdam, Netherlands.
Nabila WaliDepartment of Neurology, Amsterdam University Medical Centers, Amsterdam, Netherlands.
Stephanie Tanadini-LangDepartment of Radiation Oncology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Björn MenzeDepartment of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.
Ezequiel de la RosaDepartment of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.
Kaiyuan YangDepartment of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.
Gian Marco De MarchisDepartment of Clinical Research, University of Basel, Basel, Switzerland.
Tolga D DittrichDepartment of Clinical Research, University of Basel, Basel, Switzerland.
Francesco VallettaDepartment of Neurology and Stroke Center, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
Manon GermannDepartment of Radiology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
Carlo W CeredaStroke Center EOC, Neurocenter of Southern Switzerland, Lugano, Switzerland.
João Pedro MartoDepartment of Neurology, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal.
Lisa HerzogDepartment of Neurology, University Hospital Zurich, Zurich, Switzerland.
Patrick HirschiClinical Data Platform for Research, University Hospital Zurich, Zurich, Switzerland.
Zsolt KulcsarDepartment of Neuroradiology, University Hospital Zurich, Zurich, Switzerland.
Susanne WegenerDepartment of Neurology, University Hospital Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The Multicentre Acute ischemic stroke imaGIng and Clinical data (MAGIC) repository is a collaboration established in 2024 by seven stroke centres in Europe. MAGIC consolidates clinical and radiological data from acute ischemic stroke (AIS) patients who underwent endovascular therapy, intravenous thrombolysis, a combination of both, or conservative management. Participants: All centres ensure accuracy and completeness of the data. Only patients who did not refuse use of their routine data collected during or after their hospital stay are included in the repository. Approvals or waivers are obtained from the responsible ethics committees before data exchange. A formal data transfer agreement (DTA) is signed by all contributing centres. The centres then share their data, and files are stored centrally on a safe server at the University Hospital Zurich. There, patient identifiers are removed and images are algorithmically de-faced. De-identified structured clinical data are connected to the imaging data by a new identifier. Data are made available to participating centres which have entered into a DTA for stroke research projects. Repository setup: Initially, MAGIC is set to comprise initial and first follow-up imaging of 2,500 AIS patients. Clinical data consist of a comprehensive set of patient characteristics and routine prehospital metrics, treatment and laboratory variables. Outlook: Our repository will support research by leveraging the entire range of routinely collected imaging and clinical data. This dataset reflects the current state of practice in stroke patient evaluation and management and will enable researchers to retrospectively study clinically relevant questions outside the scope of randomized controlled clinical trials. New centres are invited to join MAGIC if they meet the requirements outlined here. We aim to reach approximately 10,000 cases by 2026.

Indexed as

collaborationdata sharingischemic strokeneuroimagingneurologyrepository

Identifiers

PMID39839853
PMCPMC11747442

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.