Evidence map›Paper›PMID 39839723›Full record

ArticleJournal of toxicologic pathology2025

Lymphangiomas with the presence of erythrocytes in mesenteric lymph nodes of Wistar Hannover rats.

Yuumi Awazuhara, Yuki Tomonari, Hiroko Kokoshima, Yumi Wako, Takuya Doi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of toxicologic pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuumi AwazuharaPathology Department, Kashima Laboratories, Non-clinical Business Segment, Mediford Corporation, Kamisu-shi, Ibaraki 314-0255, Japan.
Yuki TomonariPathology Department, Kashima Laboratories, Non-clinical Business Segment, Mediford Corporation, Kamisu-shi, Ibaraki 314-0255, Japan.
Hiroko KokoshimaPathology Department, Kashima Laboratories, Non-clinical Business Segment, Mediford Corporation, Kamisu-shi, Ibaraki 314-0255, Japan.
Yumi WakoPathology Department, Kashima Laboratories, Non-clinical Business Segment, Mediford Corporation, Kamisu-shi, Ibaraki 314-0255, Japan.
Takuya DoiPathology Department, Kashima Laboratories, Non-clinical Business Segment, Mediford Corporation, Kamisu-shi, Ibaraki 314-0255, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We performed morphological and immunohistochemical analyses of erythrocyte-rich vascular proliferative lesions of mesenteric lymph nodes in six male and one female Wistar Hannover rats. These lesions are conventionally diagnosed as hemangiomas due to abundant erythrocytes. Immunostaining was positive for prospero-related homeobox 1 (Prox-1) and/or vascular endothelial growth factor receptor 3 (VEGFR3) in all lesions, suggesting a lymphangitic origin. In 6 of 7 lesions, von Willebrand factor (vWF) immunostaining was negative, suggesting a non-blood vascular origin. These results demonstrated that almost all hemangiomas in rat mesenteric lymph nodes were lymphangiomas. To the best of our knowledge, this is the first report highlighting the lymphatic origin of vascular proliferative lesions in the mesenteric lymph nodes of rats.

Indexed as

hemangiomalymphangiomamesenteric lymph nodeprospero-related homeobox 1 (Prox-1)ratvascular endothelial growth factor receptor 3 (VEGFR3)

Identifiers

PMID39839723
PMCPMC11745497

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.