ReviewJournal of Taibah University Medical Sciences2025
Roles of calcium in ameloblasts during tooth development: A scoping review.
Review in Journal of Taibah University Medical Sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Nanoparticle Saltwater Fish Powder and Cell Protein Pathways in Enamel Density Enhancement.European journal of dentistry · 2026Article
- Human Enamel Formation: A Scoping Review for Oral Health Professionals.Dentistry journal · 2026Review
- [Oral homeostasis imbalance under hypoxia].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026Review
- Impact of perinatal risk factors on developmental defect of enamel and dental caries in primary teeth of high-risk infants: a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Calcium ions (Ca Methods: This scoping review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The literature search, conducted in December 2023, spanned multiple databases including PubMed (8.363 records), Google Scholar (5.630 records), and Science Direct (21.810 records). The primary aim was to examine the influence of calcium ion regulation on ameloblast development, with a focus on preclinical studies. Results: After an initial screening of 396 titles and abstracts, 11 full-text articles (four Conclusion: Calcium transport mechanisms play a critical role in enamel formation, with factors such as TRPM7, Kir 4.2, CRAC channels, and the SOCE pathway supporting enamel mineralization, while disruptions like hypoxia, fluoride exposure, and circadian imbalances negatively impact amelogenesis. Understanding the interplay between calcium, environmental, and nutritional factors provides valuable insights into ameloblast function and offers potential avenues for improving enamel quality and addressing defects.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.