ArticlePediatric gastroenterology, hepatology & nutrition2025
Platelet Count at Diagnosis Is Associated with Endoscopic Activity in Pediatric Patients with Crohn's Disease.
Article in Pediatric gastroenterology, hepatology & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: We aimed to evaluate the association between platelet count and endoscopy activity in pediatric patients with Crohn's disease (CD). Methods: This single center retrospective study included children and adolescents aged <19 years who were newly diagnosed with CD. Comparison of baseline characteristics at diagnosis between two groups divided according to the presence and absence of thrombocytosis were conducted. Factors associated with moderate-to-severe endoscopic activity was also conducted. Results: A total of 50 were included. Thirty-five patients (70.0%) were male, and the mean age±standard deviation was 13.7±2.5 years. Among patients without thrombocytosis, endoscopic activity was mild in 9 patients (42.9%), moderate in 11 (52.4%), and severe in 1 (4.8%), while among patients with thrombocytosis, endoscopic activity was mild in 3 (10.3%), moderate in14 (48.3%), and severe in 12 (41.4%) ( Conclusion: Pediatric patients with CD that present with thrombocytosis at diagnosis are likely to have a moderate-to-severe endoscopic activity.
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