ArticleAlzheimer's & dementia (New York, N. Y.)
Dynamic neurocognitive adaptation in aging: Development and validation of a new scale.
Article in Alzheimer's & dementia (New York, N. Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07533084 (Italian Validation of the Dynamic Neurocognitive Adaptation), which is not on this map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Italian Validation of the Dynamic Neurocognitive Adaptation (dNA) Scale and Its Correlation With Neurocognitive Variables
Who cites it
3 citing papers in PubMed.
- Dynamic neurocognitive adaptation: childhood and adult-midlife engagement associated with later-life brain structure and cognition in older adults with and without mild cognitive impairment.Brain imaging and behavior · 2026Article
- Dynamic neurocognitive adaptation in aging: Development and validation of a new scale.Alzheimer's & dementia (New York, N. Y.)Article
- Dynamic neurocognitive adaptation: A follow-up exposome investigation in aging.Alzheimer's & dementia (New York, N. Y.)Article
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Authors and funding
5 authors.
Funding
Abstract
introductionForty-five percent of Alzheimer's disease (AD) cases may have been preventable through protective factors. Reserve, resilience, and resistance share common neurocognitive adaptive processes, acting through protective mechanisms. In this article we propose the development and validation of a new scale, called dynamic Neurocognitive Adaptation, developed in this direction.
methodsWe included 815 participants (50% women; 65+ years inclusive of age), divided into two subsamples for exploratory and confirmatory factor analysis. Our initial scale was composed of 30 items, investigating seven dimensions, explored by a 5-point Likert scale reflecting the frequency of activities, for seven time windows.
resultsOur final scale had 20 items divided among four dimensions: physical, cognitive, creative, and social. There were no issues related to multi-collinearity or non-collinearity. Kaiser-Meyer-Olkin (KMO) = 0.80 and Bartlett's test of sphericity indicated all values ≤0.01; Cronbach's alpha = 0.83. DISCUSSION: We have validated a reliable, novel, easy to complete, and comprehensive scale to assess lifetime behaviors, which can be applied in research on AD risk reduction, mild cognitive impairment, and in clinical practice. Highlights: Reserve, resistance, and resilience share similar adaptive mechanisms.Dynamic Neurocognitive Adaptation is a new scale to assess lifetime protective factors.Dynamic Neurocognitive Adaptation is a reliable, novel, and easy to complete scale.This approach can characterize specific life stages that are ripe for risk-reduction interventions.Our scale can be used to personalize health recommendations in aging.
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