ArticleQuantitative imaging in medicine and surgery2025
The rotation method for correcting renal depth in the determination of glomerular filtration rate using Tc-99m diethylenetriamine pentaacetic acid (DTPA)-based renal dynamic imaging in patients with hydronephrosis.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Kidney depth significantly affects the accuracy of glomerular filtration rate (GFR) measurement, and hydronephrosis-induced morphological changes further challenge its estimation through traditional formulas. This study evaluated the rotation method's efficacy in correcting kidney depth and depth difference during Tc-99m diethylenetriamine pentaacetic acid (DTPA) renal dynamic imaging for GFR assessment. Methods: This study analyzed 66 individuals treated at First Hospital of Shanxi Medical University with unilateral hydronephrosis between January 2022 and June 2023. Abdominal computed tomography (CT) scans were used to classify hydronephrosis severity into mild (20 cases), moderate (23 cases), and severe hydronephrosis groups (23 cases). Depth and depth differences of the kidneys were measured using CT, the rotation method, the Tonnesen formula, and the Li-Qian formula to evaluate their impact on total and single-kidney GFR. Results: (I) Regarding renal depth and GFR, compared to CT, the Tonnesen formula underestimated both the depth and GFR for normal and hydronephrotic kidneys (NKs and HKs). The mean depth of normal kidneys (NKs) measured by the Tonnesen formula was 6.14 cm, approximately 19% lower than the 7.59 cm measured by CT. Similarly, the GFR of NKs estimated by the Tonnesen formula was 37.13 mL/min/1.73 m Conclusions: In patients with hydronephrosis, the renal depth and depth difference measured by the rotation method are similar to those measured by CT, which can accurately correct the renal depth and depth difference without increasing the patient's additional radiation, enhancing the precision of total and separate renal GFR.
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