Evidence map›Paper›PMID 39838999›Full record

ArticleQuantitative imaging in medicine and surgery2025

Ting Yang, Yuan Yang, Siqi Hu, Yujie Xie, Zijie Shen, Yong Zhang

Abstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Diagnostics (Basel, Switzerland) · 2026
    Article
  2. Performance of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ting Yang *Department of Nuclear Medicine, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yuan Yang *Department of Nuclear Medicine, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Siqi HuDepartment of Nuclear Medicine, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yujie XieDepartment of Nuclear Medicine, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Zijie ShenDepartment of Nuclear Medicine, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yong ZhangDepartment of Nuclear Medicine, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Accurately differentiating hepatocellular carcinoma (HCC) from intrahepatic cholangiocarcinoma (ICC) is essential for therapeutic decision-making. This study aimed to explore the value of Fluor 18 ( Methods: Patients with suspected intrahepatic lesions who underwent Results: A total of 48 patients (age 55.4±10.8 years; 35 males and 13 females), including 28 in the HCC and 20 in the ICC group, were included. Univariate analysis revealed significant differences in clinical indicators such as gender, platelet count, and hepatitis B surface antigen, carbohydrate antigen 19-9 (CA19-9), and alpha fetoprotein (AFP) levels between the groups (P<0.05). Metabolic parameters including the maximum standardized uptake value (SUVmax), the total lesion-FAPI (TL-FAPI), and the target-to-background ratio (TBR) were statistically different between groups (P<0.01), and patients with ICC had higher values than those with HCC, while the FAPI tumor volume (FAPI-TV) was not statistically different (P>0.05). Multivariate binary logistic regression analysis identified the SUVmax (P=0.003) as an independent predictor for ICC, and the AUC of the regression-based diagnostic model for predicting ICC was 0.914 at an optimal cutoff value of 12.13, with a sensitivity of 85.0% and a specificity of 89.3%. Conclusions: SUVmax is an independent predictor for ICC. With the optimal cutoff value of 12.13,

Indexed as

Fibroblast-activation protein inhibitor (FAPI)hepatocellular carcinoma (HCC)intrahepatic cholangiocarcinoma (ICC)maximum standardized uptake value (SUVmax)positron emission tomography-computed tomography (PET/CT)

Identifiers

PMID39838999
PMCPMC11744148

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.