ArticleQuantitative imaging in medicine and surgery2025
Radiological findings in children with primary mediastinal Ewing sarcoma/primitive neuroectodermal tumors: a retrospective case series study.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The goal of this study was to summarize the radiological findings and clinical characteristics of mediastinal Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET) in children. A retrospective review was conducted on the clinical and imaging data of 6 children with primary mediastinal ES/PNET that was confirmed by pathology. There were 3 girls and 3 boys in this study, aged between 2 and 11 years old. The tumors exhibited a range of maximum diameters for each child, spanning from 3.8 to 16.0 cm, and the boundaries of 6 tumors were unclear. Furthermore, the tumors were located in the posterior mediastinum in 2 cases, in the mid-posterior mediastinum in 3 cases, and in the anterior middle posterior mediastinum in 1 case. Necrosis and cystic degeneration were found in all 6 cases, and calcification was found in 2 cases, and the solid part of the tumors showed moderate heterogeneous progressive enhancement. The spinal epidural was involved in 2 cases; adjacent ribs were invaded in 2 cases; the adjacent vertebral body and appendage were invaded in 1 case, and the chest wall was invaded in 4 cases. Finally, pleural effusion occurred in 4 cases, including 1 case with pericardial effusion; 3 patients with pleural metastasis. In conclusion, the computed tomography (CT) findings of primary ES/PNET originating in childhood show a level of distinctiveness that facilitates their identification.
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