Evidence map›Paper›PMID 39838971›Full record

ArticleAmerican journal of preventive cardiology2025

Association of neighborhood-level socioeconomic disadvantage and Life's Essential 8 in early pregnancy.

Kartik K Venkatesh, William A Grobman, Xiaoning Huang, Lynn M Yee, Janet Catov, Hy Simhan, David M Haas, Brian Mercer, Uma Reddy, Robert M Silver and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of preventive cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Kartik K VenkateshDepartment of Obstetrics and Gynecology, The Ohio State University, Columbus, OH, USA.
William A GrobmanDepartment of Obstetrics and Gynecology, The Ohio State University, Columbus, OH, USA.
Xiaoning HuangDepartment of Preventive Medicine, Northwestern University, Chicago, IL, USA.
Lynn M YeeDepartment of Obstetrics and Gynecology, Northwestern University, Chicago, IL, USA.
Janet CatovDepartment of Obstetrics and Gynecology, University of Pittsburgh, Pittsburgh, PA, USA.
Hy SimhanDepartment of Obstetrics and Gynecology, University of Pittsburgh, Pittsburgh, PA, USA.
David M HaasDepartment of Obstetrics and Gynecology, Indiana University, Indianapolis, IN, USA.
Brian MercerDepartment of Obstetrics and Gynecology, Case Western Reserve University, Cleveland, OH, USA.
Uma ReddyDepartment of Obstetrics and Gynecology, Columbia University, New York, NY, USA.
Robert M SilverDepartment of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT, USA.
Lisa D LevineDepartment of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA, USA.
Judith ChungDepartment of Obstetrics and Gynecology, University of California, Irvine, Orange, CA, USA.
George SaadeDepartment of Obstetrics and Gynecology, Eastern Virginia Medical College, Norfolk, VA, USA.
Philip GreenlandDepartment of Preventive Medicine, Northwestern University, Chicago, IL, USA.
C Noel Bairey MerzBarbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA.
Becky McNeilRTI International, Durham, NC, USA.
Sadiya S KhanDepartment of Preventive Medicine, Northwestern University, Chicago, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We examined whether neighborhood-level socioeconomic disadvantage per the Area Deprivation Index (ADI) was associated with maternal cardiovascular health (CVH) in early pregnancy per the American Heart Association Life's Essential 8 (LE8). This is a cross-sectional analysis from the prospective Nulliparous Pregnancy Outcomes Study-Monitoring Mothers-to-Be Heart Health Study (nuMoM2b-HHS) cohort. The exposure was the ADI in tertiles (T) from least (T1) to most (T3) socioeconomic disadvantage. The outcome was the LE8 as a continuous score ranging from worst (0) to best (100) composite CVH; and included physical activity, diet quality, tobacco use, sleep quantity, body mass index, blood pressure, glucose, and lipid levels. Among 4,508 nulliparous individuals at a mean maternal age of 27.0 years (SD: 5.6) and at a mean gestational age of 11.4 weeks (SD 1.6), the mean ADI was 48.0 (SD: 30.4) and the mean LE8 was 80.3 (SD: 12.5). Pregnant individuals living in neighborhoods with greater socioeconomic disadvantage had lower mean LE8 scores (i.e., worse CVH) compared with those living in neighborhoods with lesser disadvantage (T1 vs. T2 adjusted mean: 82.6 vs. 80.5; adj. ß:2.08; 95 % CI:3.51, -0.64; and T1 vs. T3 adjusted mean: 82.6 vs. 77.8; adj. ß:4.77; 95 % CI:8.16, -1.38). Neighborhood-level socioeconomic disadvantage was associated with worse maternal CVH in early pregnancy.

Indexed as

Area deprivation indexCardiovascular healthLife's Essential 8PregnancySocial determinants of health

Identifiers

PMID39838971
PMCPMC11750432

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.